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N112 - Angiotension II Receptor Blockers for test 1

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Question
Answer
ARBs   Antiotension II receptor Blocker or Antagonist  
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Uses   Used alone or in combination with other medication to treat HTN (hypertension)  
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Other uses   Adjunctive agent to treat CHF (congestive heart failure)  
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Action   blocks the action of angiotensin II after it is formed, ARBs block receptors for angiotensin II in vascular smooth muscle & adrenal glands (competitive inhibition) = block vasoconstriction & secretion of aldosterone  
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Side effects/Adverse reactions   Headache, upper respiratory infection, dizziness, Does not cause cough of ACE inhibitors, Does not cause hyperkalemia (K+)  
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Nursing consideration 1   Monitor vital signs especially BP  
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Nursing consideration 2   May take with or without food  
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Nursing consideration 3   Advise patient to change position slowly to avoid orthostatic hypotension  
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Evaluate effectiveness of the drug   Decreased BP, improvement in s/s of CHF (congestive heart failure)  
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Drug to drug interactions   Lithium toxicity, Tagamet = decrease effectiveness of ARBs  
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