MSK Derm 1
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| What makes up the unhappy triad in a knee injury? | Damage to ACL, MCL & medial meniscus Caused by clipping from the lateral side
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| What are the rotator cuff muscles? | SITS Supraspinatus, Infraspinatus, Teres minor, Subscapularis
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| Failure of longitudinal bone growth leads to short limbs | Achondroplasia
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| Heberden's & Bouchard's nodes | Heberdon's-DIP; Bouchard's-PIP a/w osteoarthritis
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| Failure of normal bone resorption leads to thickened, dense bones | Osteopetrosis
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| "Brown tumors" | a/w Osteitis fibrosa cystica- caused by hyperparathyroidism
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| Abnormal bone architecture caused by increase in both osteoblastic & osteoclastic activity | Paget's disease of the bone
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| Bone is replaced by fibroblasts, collagen & irregular bony trabeculae | Polyostotic fibrous dysplasia
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| Joint problem a/w temporal arteritis | Polymyalgia rheumatica
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| Progressive symmetric proximal muscle weakness caused by CD8+ T-cell-induced injury to myofibers | Polymyositis
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| Polymyositis w/ "shawl & face" skin rash & increased risk of malignancy | Dermatomyositis
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| Antibodies to U1RNP | Mixed connective tissue disease
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| Dry eyes, dry mouth & arthritis | Sjogren's syndrome
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| a/w rheumatoid arthritis & dental carries | Sjogren's syndrome
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| Autoantibodies to SS-A(Ro) & SS-B(La) | Sjogren's syndrome
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| Monosodium urate crystals | Gout
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| Calcium pyrophosphate crystals | Pseudogout
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| a/w elevated levels of ACE | Sarcoidosis
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| Joint problem a/w uveitis & aortic regurgitation | Ankylosing spondylitis
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| Triad of: Urethritis, Conjunctivitis & anterior uveitis, Arthritis | Reiter's syndrome "Can't see, can't pee, can't climb a tree"
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| What is CREST syndrome | Calcinosis, Raynaud's phenomenon, Esophageal dysmotility, Sclerodactyly & Telangiectasia
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| Dysplastic nevus is a precursor to what? | Melanoma
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| Most common benign bone tumor | Osteochondroma
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| Bone tumor w/ interlacing trabeculae of woven bone surrounded by osteoblasts; <2cm | Osteoid osteoma
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| Bone tumor w/ interlacing trabeculae of woven bone surrounded by osteoblasts; >2cm | Osteoblastoma
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| Bone tumor w/ "double bubble" or "soap bubble" appearance on x-ray | Giant cell tumor
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| Bone tumor that is a cartilaginous neoplasm found in intramedullary bone of distal extremities | Enchondroma
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| Most common primary malignant tumor of bone | Multiple myeloma or Osteosarcoma depending on the source
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| Bone tumor w/ Codman's triangle on x-ray | Osteosarcoma
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| Bone tumor w/ anaplastic small blue cells | Ewing's sarcoma
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| Bone tumor w/ "Onion skin" appearance in bone | Ewing's sarcoma
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| Bone tumor a/w t(11;22) | Ewing's sarcoma
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| Malignant cartilaginous bone tumor | Chondrosarcoma
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| Expansile glistening mass within the medullary cavity | Chondrosarcoma
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| Bone tumor w/ peak incidence of 20-40 years old | Giant cell tumor
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| Bone tumor that is most common in men <25 years old | Osteochondroma
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| Bone tumor w/ peak incidence in men of 10-20 years old | Osteosarcoma
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| Tumor caused by t(x;18) | Synovial sarcoma
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| Bone tumor that is most common in boys <15 years old | Ewing's sarcoma
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| Bone tumor that is most common in men 30-60 years old | Chondrosarcoma
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| Vasculitis seen commonly in heavy smokers | Beurger's disease
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| Vasculitis known as "pulesless disease" | Takayasu's arteritis
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| Vasculitis that primarily affects asian females <40 years old | Takayasu's arteritis
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| Vasculitis w/ unilateral headache, jaw claudication & impaired vision | Temporal arteritis
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| Vasculitis a/w Hepatitis B | Polyarteritis nodosa
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| Vasculitis that affects renal & visceral veins w/ lesions of different ages | Polyarteritis nodosa
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| Triad of vasculitis, granulomas in lungs & airway, & glomerulonephritis | Wegener's granulomatosis
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| Vasculitis that is an acute, self-limiting disease of infants/kids | Kawasaki disease
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| Most common form of childhood systemic vasculitis | Henoch-Schonlein purpura
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| Skin rash, arthralgia, intestinal hemorrhage, abdominal pain & melena in kids | Henoch-Schonlein purpura
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| AV malformation in small vessels | Telangiectasia
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| ANA | Antinuclear antibody a/w SLE
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| Anti-dsDNA | Anti double stranded DNA a/w SLE(more specific than ANA)
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| Anti-Smith | a/w SLE (more specific than ANA)
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| Anti-histone | a/w Drug-induced lupus
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| Anti-IgG | aka Rheumatoid factor a/w Rheumatoid arthritis
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| C-ANCA | Antineutrophil cytoplasmic Ab a/w Vasculitis
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| P-ANCA | Antineutrophil cytoplasmic Ab a/w Vasculitis
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| Anticentromere | a/w Scleroderma (CREST)
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| Anti-Scl-70 | a/w Scleroderma (Diffuse)
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| Anti-epithelial cell | a/w Pemphigus vulgaris
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| Anti-Jo-1 | a/w Polymyositis & dermatomyositis
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| HLA a/w: Ankylosing spondylitis | HLA-B27
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| HLA a/w: Reiter's Syndrome | HLA-B27
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| HLA a/w: SLE | HLA-DR2
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| HLA a/w: Rheumatoid Arthritis | HLA-DR4
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