Medication Classification Definitions
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| Alpha Receptors | Activates enzymes inside plasma membrane.
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| Alpha 1 | Releases intracellular calcium ions into the cytosol from reserves in endoplasmic reticulum. Causes vasoconstriction, increased contractile force, decreasing heart rate, bronchoconstriction.
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| Alpha 2 | Lowers cyclic AMP (cAMP) levels in cytoplasm. cAMP is a 2nd messenger that can activate/inactivate key enzymes. Vasodilatation, decreases blood pressure, in targeted organs, coronary arteries.
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| Beta Receptors | Located in membranes of cells in organs, including skeletal muscles, lungs, heart, liver. Changes metabolic activity in cell by stimulation, resulting in increase in intracellular cAMP levels.
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| Beta 1 | Increases metabolic activity, in skeletal muscles, accelerates in the heart, increase in heart rate and contraction force.
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| Beta 2 | Causes inhibition, triggering a relaxation of smooth muscles along respiratory tract, respiratory passageways open, making breathing easier. Bronchodilation.
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| Beta 3 | Stimulation leads to lipolysis, breakdown of triglycerides.
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| Agonist | medication or other substance that binds with a specific medication receptor and causes a physiological response.
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| Antagonist | medication or other substance that blocks a physiological response that blocks the action of another medication or substance.
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| Adrenergic | related to the SNS, receptors specific to norepinephrine and epinephrine-like substances
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| Pressor | Base substance capable of raising blood pressure, reflex is a nerve causing constriction of arterioles increasing blood pressure.
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| Sympathomimetic | medication or other substance that causes effects such as those of the SNS (adrenergic)
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| Sympatholytic | medications blocking beta adrenergic receptors and slow heart rate
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| Parasympathomimetics | medications stimulating the parasympathetic nerve system
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| Parasympatholytic | Medications that inhibit the parasympathetic nerve system
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| Chronotrophy | change the heart rate by affecting the nerves controlling the heart, or by changing the rhythm produced by the sinoatrial node. Positive chronotropes increase heart rate; negative chronotropes decrease heart rate.
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| Dromotrophy | affects the conduction speed in the AV node, and subsequently the rate of electrical impulses in the heart
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| Inotrophy | alters the force or energy of muscular contractions.
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Created by:
JCowie024
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