Real Immuno 1
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| show | Right arm and right half of head
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| show | Everything except for the right arm and the right half of head
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| show | Long, vascular channels in red pulp with fenestrated "barrel hoop" basement membrane and macrophages nearby. Adjacent to splenic cords and contain blood.
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| How can the spleen be distinguished from a lymph node on histologic section? | show 🗑
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| What does the white pulp of the spleen contain? | show 🗑
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| Where is the red pulp of the spleen located? | show 🗑
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| Splenic cords: What are they? | show 🗑
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| show | Site of T-cell differentiation and maturation (T cells differentiate in the Thymus. B cells differentiate in the Bone marrow)
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| Thymus: Embryological origin | show 🗑
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| Lymphocytes: Embryological origin | show 🗑
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| show | The lobules resemble lymphatic nodules except they are angular, not round.
Contains:
1. Densely packed (dark) immature T cells.
2. Large epithelial reticular cells which appear as holes within the cortical cells.
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| show | Pale Contains: Thymic (Hassall's) corpuscles which have a lamellated or whorled appearance due to degenerating epithelial reticular cells.
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| What percentage of T cells which enter thymus survive? | show 🗑
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| What is positive selection of T cells? | show 🗑
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| show | At the corticomedullary junction
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| show | MCH/self antigen presented again. Selects against T-cells that react to strongly to the self-antigen. Binding self too tightly triggers apoptosis signal.
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| show | Innate: Germline encoded
Adaptive: Undergo VDJ recombination during development
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| show | Innate: Always fast, no memory response.
Adaptive: Slow on 1st exposure but memory response is faster and more robust.
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| Innate immunity or adaptive immunity: Neutrophils | show 🗑
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| show | Innate immunity
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| show | Innate immunity
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| show | Innate immunity
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| Innate immunity or adaptive immunity: T cells | show 🗑
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| Innate immunity or adaptive immunity: B cells | show 🗑
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| Innate immunity or adaptive immunity: Circulating antibody | show 🗑
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Created by:
Asclepius
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