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Test 1

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Peripheral Nervous System (PNS) divides into   Somatic and Visceral  
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Somatic division uses   Voluntary: Skeletal muscles  
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Visceral division (Autonomic Nervous System [ANS])uses   Involuntary: Smooth and Cardiac muscles  
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Visceral system (ANS) is divided into the   Sympathetic nervous system and Parasympathetic nervous system  
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Sympathetic response is   Fight or Flight (or Freeze)  
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Parasympathetic response is   Rest and Digest  
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Which division of the ANS is the default state of the body?   Parasympathetic  
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What is the main neurotransmitter of the Sympathetic nervous system?   Norepinephrine (NE)  
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What is the main neurotransmitter of the Parasympathetic nervous system?   Acetylcholine (ACH)  
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Where does Norepinephrine (NE) come from?   Nerve endings of the Sympathetic nervous system. Nor=neuron Epi=above nephrine=kidney  
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Where does Epinephrine (EPI) come from?   Adrenal glands on top of the kidneys. Epi=above nephrine=kidney  
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Is epinephrine a hormone?   Yes  
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Is norepinephrine a hormone?   No  
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Will the sympathetic nervous respond to epinephrine (EPI)   Yes  
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Sympathetic effect on the Adrenal Medulla   Release of Epinephrine (EPI)  
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Parasympathetic effect on Adrenal Medulla   Nothing  
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Sympathetic effect on Arteries   Vasoconstriction (exceptions are the coronoary arteries to the heart and skeletal muscles which are dilated)  
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Parasympathetic effect on Arteries   Most arteries are not supplied by parasympathetic nerves  
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Sympathetic effect on Blood Pressure   Increase BP  
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Parasympathetic effect on Blood Pressure   Decrease BP  
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Sympathetic effect on the Heart   Increases contractility  
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Parasympathetic effect on the Heart   Decreases contractility  
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Sympathetic effect on Heart Rate (HR)   HR increase  
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Parasympathetic effect on Heart Rate (HR)   HR decrease  
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Sympathetic effect on Peristalsis and Digestion   Decreased Motility and Secretions  
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Parasympathetic effect on Peristalsis and Digestion   Increased Motility and Secretions  
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Sympathetic effect on the Eye   Pupils Dilate  
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Parasympathetic effect on the Eye   Pupils Constrict  
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Sympathetic effect on Lungs   Broncho-Dilation  
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Parasympathetic effect on Lungs   Broncho-Constriction  
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Sympathetic effect on Bladder   Relaxation  
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Parasympathetic effect on Bladder   Constriction  
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Sympathetic effect on the Urinary Sphincter   Contraction  
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Parasympathetic effect on the Urinary Sphincter   Relaxation  
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Sympathetic effect on Smooth Muscle   Constriction  
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Parasympathetic effect on Smooth Muscle   Relaxation  
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Where is Smooth Muscle located?   Every organ: intestine lining, bladder, uterus, ureter, veins, arteries, lungs, mucous membranes...  
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Sympathetic receptor site   Adrenergic Receptor Site  
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Parasympathetic receptor site   Cholinergic Receptor Site  
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Beta 1 receptor sites are located in   Cardiac muscles (Heart) only  
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Beta 2 receptor sites are located in   Smooth muscles  
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Alpha receptor sites are located in   Smooth muscles of the Arteries, Veins, Capillaries, and Blood Vessels.  
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As people age the production of ACH   Decreases  
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A decrease in the production of ACH may cause   Constipation  
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Alzheimer's Disease might be attributed to a lack of   ACH  
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Stress and Anxiety can activate the   Sympathetic Nervous System  
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Prolonged activation of the Sympathetic Nervous System (stress/anxiety) can cause   Weight Gain, Increased Blood Pressure, and Hypertension  
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Meth and Cocaine are considered   Sympathomimetics (resemble EPI)  
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Effects of Meth   Appetite Suppressed, weight loss, teeth loss (due to enamel strip), temporary drug induced schitzophrenia  
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What type of relationship does the Sympathetic Nervous System and the Parasympathetic Nervous System have with each other?   Inverse relationship (negative). As one goes up the other goes down. As one gown down the other will go up. Always seeking equilibrium (balance).  
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Visceral is a Latin for   Internal  
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What is a neurotransmitter?   Chemical Messenger. A substance that stimulates internal organs to produce characteristic changes associated with sympathetic and parasympathetic divisions.  
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Role of Serotonin   Mood, Appetite, Libido, Sleep, and Arousal (wakefulness)  
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Role of Dopamine   Limbic system (reward), voluntary decision making, Motor (skeletal) Muscle movement. Acts as a vasodilator. Inhibits NE.  
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Role of Norepinephrine (NE)   Increases Blood Pressure, Increases Heart Rate, Increase Anxiety States, Increase Manic State, and affects mood  
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What happens when NE levels are high?   Possible Mania, Cardiac Problems, and Schizophrenia  
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Role of Acetylcholine (ACH)   sleep, arousal, pain perception, modulation and coordination of movement and memory retention  
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What happens when ACH levels are high?   Possible Depression  
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The parasympathetic division is more active during digestion and elimination of waste products and when the body is at   rest  
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NE does not stimulate   Beta 2 receptor sites  
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EPI stimulates   Beta 1, Beta 2, and Alpha receptor sites  
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Adrenergic receptors accept   NE and EPI  
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Adrenergic receptors are classified as   Beta-adrenergic or Alpha-adrenergic  
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Alpha-adrenergic receptors are found mainly on   Smooth muscle membranes: small arteries, capillaries, and small vessels  
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Alpha-adrenergic blocking drugs are used to clinically cause   Vasoconstriction of blood vessels  
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In hypotensive states, drugs such as norepinephrine, and metaraminol, are given by IV injection to   Raise Blood Pressure  
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Levophed   Norepinephrine  
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Mimetics   do the same as the real thing (mimic)  
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Lytics   slow down effects (inhibit)  
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Blockers   act as antagonist (interferes with drugs or substance from producing a drug effect)  
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Alpha adrenaline blocking drugs are used clinically to   Lower Blood Pressure in Hypertension and Increase Urine Flow in benign pro static hyperplasia  
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Alpha drugs are usually administered   orally  
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Common adverse effects of alpha-adrenergic blocking drugs include:   Nasal Congestion, Blurred Vision due to pupil constriction, increased GI activity  
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Excessive lowering of blood pressure may cause:   hypotension, fainting, and reflex tachycardia  
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Prazosin   Minipress  
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Prazoson(Minipress) is a   Alpha-Adrenergic Blocker  
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Prazosin(Minipress) is used to treat   high blood pressure. It works by relaxing blood vessels.  
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Doxazosin   Cardura  
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Doxazosin(Cardura) is a   Alpha-Adrenergic Blocker  
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Doxazosin(Cardura) is used to treat   symptoms of enlarged prostate in men, and high blood pressure. It works by relaxing muscles in prostate, bladder, and blood vessels.  
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Beta-Adrenergic drugs are used clinically to   Stimulate the heart. Bronchodilation. Relax uterus during preterm labor.  
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Selective Beta-2 adrenergic drugs are usually administered by   oral inhalation for the control of Asthma  
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Epinephrine is injected sub Q in   allergic and cardiac emergencies  
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Dopamine   Intropin  
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Epinephrine   Adrenaline  
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Both Dopamin(Intropin) and Epinephrine(Adrenaline) are   Beta-adrenergic drugs  
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Norepinephrine(Levophed) is a   Alpha-adrenergic drug  
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Both Prazoson(Minipress) and Doxazosin(Cardura) are   Alpha-adrenergic blocking drugs  
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Propranolol(Inderal)   Beta-Adrenergic (Nonselective) Blocking Drug  
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Atenolol(Tenormin)   Beta-Adrenergic (Selective Beta-1) Blocking Drugs  
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Epinephrine(Adrenaline) is classified as a   Alpha-adrenergic agonist and Beta-adrenergic agonist. Sympathomimetic agents.  
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Beta-adrenergic blocking drugs are used for their   Beta-1 blocking activity  
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Beta-1-adrenergic blocking drugs are used to treat   Hypertension. Angina Pectoris. Tachycardia. After a myocardial infarction (MI) to reduce mortality.  
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The most serious adverse effect of beta blocking drugs   reduced heart function (bradycardia). May lead to congestive heart failure or cardiac arrest  
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In asthmatics, non selective beta-adrenergic blockers may cause   Bronchoconstriction  
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Propranolol   Inderal  
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Propranolol(Inderal) warning   May cause heart attack or chest pain if stopped suddenly.  
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Propranolol(Inderal) is used to treat   High blood pressure. Abnormal heart rhythms. Heart Disease. Prevents Angina and prevents migraine headache.  
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Propranolol(Inderal) works by   relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.  
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Atenolol   Tenormin  
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Atenolol(Tenormin) warning   May cause heart attack, chest pain, or irregular heartbeat if stopped suddenly.  
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Atenolol(Tenormin) is used to treat   High blood pressure. Prevent angina. Improve survival after a heart attack.  
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Atenolol(Tenormin) works by   Relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.  
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NE and EPI are inactivated by   reuptake and metabolism by Monoamine Oxidase (MAO)  
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Alpha receptor stimulation causes   Vasoconstriction and Pupil Dilation  
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Adverse affects of Alpha-adrenergic drugs   excessive vasoconstriction which leads to hypertension and excessive dryness of the eyes and nasal sinuses  
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Overstimulation with Beta-adrenergic drugs can cause   excessive cardiac stimulation and increased blood pressure  
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Adrenergic drugs can cause CNS stimulation resulting in   Tremors, Restlessness, and Anxiety  
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Adrenergic neuronal blockers decrease the synthesis and release of   Norepinephrine  
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Sympathomimetic   Stimulates the Sympathetic Nervous System  
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Sympatholytic   Slows down or inhibits the Sympathetic Nervous System  
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Parasympathomimetic   Stimulates the Parasympathetic Nervous System  
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Parasympatholytic   Slows down or inhibits the Parasympathetic Nervous System  
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3 types of Cholinergic receptors   Muscarnic, Nicotinic, and Nicotinic-Neutral  
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Cholinergic crisis   Too much ACH. Respiratory paralysis. Common among farmers who get sprayed by crop dusters.  
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Adverse effects of Alpha-adrenergic blocking drugs   Hupotension, sluggish feeling, and dizzy spells  
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There are no specific therapeutic indications for blocking   Beta-2 Receptors  
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Beta-adrenergic blocking drugs affect   Carbohydrate and Lipid metabolism.  
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