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Tx Rx List

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Term
Definition
Tacrolimus is also known as   Prograf, FK506  
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Tacrolimus is a ___ type medication   Anti-rejection, macrolide antibiotic with immunosupressive properties  
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Main side effects of tacrolimus include   Headaches, HTN, N/D, high BG, tremors, hair LOSS, trouble sleeping, infxn, numbness/tingling, hyperkalemia, abnormal kidney fxn  
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Cyclosporine is also known as   Sandimmune  
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Main side effects of cyclosporine include   HA, tremor, abnormal kidney fxn, HTN, high BG, high cholesterol, infxn, hyperkalemia, excessive hair GROWTH, trouble sleeping, overgrowth gums  
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Prednisone is also known as   Deltasone  
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True or false: prednisone dose might be lowered if you remain rejection free post-tx   True  
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Main side effects of prednisone include   High BG, wt gain, hunger, puffy cheeks, infxn, acne, bruising, osteoporosis, high cholesterol, mood swings, night sweats, anxiety, stomach upset, blurry vision (cataracts)  
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Mycophenolate mofetil is also known as   CellCept, MMF, MPA, RS  
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True or false: mycophenolate mofetil is a prodrug of mycophenolic acid   True  
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Mycophenolate mofetil is a inhibitor of   Inosine monophosphate dehydrogenase (IMPDH), an enzyme. This affects a pathway in B/T lymphocytes  
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Mycophenolate mofetil (MMF) can lower your WBCs as well as   Platelets  
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Main side effects of MMF include   Heartburn, stomach upset, infxn, N/V/D, neutropenia, thrombocytopenia  
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What is Imuran also called?   Azathioprine  
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Azathioprine can lower your __ and __   WBC, PLT  
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What other common med should you be cautious of combining with azathioprine?   Allopurinol  
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Main SE of azathioprine include   N/V, infxn, neutropenia, thrombocytopenia  
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Antithymocyte globulin (Atgam, Thymoglobulin) is given for what reason?   To prevent or treat acute rejection  
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Antithymocyte globulin can only be given in what route?   IV  
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Main SE of antithymocyte globulin include   Difficulty breathing, N/V/D, fever, chills, rash, muscle aches, infxn, pain during infusion  
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OKT3's purpose is   Given to treat rejection  
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OKT3 can only be given   IV  
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Precautions with OKT3 include   Wheezing, SOB, dysphagia, rapid HR, rash, itching.  
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True or false: most pt. do not have adverse rxn to OKT3 in first 3 doses   False. Common to have mild adverse reactions  
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Main SE of OKT3 include   Wheezing, difficulty breathing, CP, fever, chills, N/V/D, tremor, HA, infxn, fast HR, muscle stiffness  
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Daclizumab/Basiliximab is a medication that suppresses immune system amd is given in what route at what time?   IV, at time of tx and 2x more days 4 and 14  
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