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Tx Rx List

Tacrolimus is also known as Prograf, FK506
Tacrolimus is a ___ type medication Anti-rejection, macrolide antibiotic with immunosupressive properties
Main side effects of tacrolimus include Headaches, HTN, N/D, high BG, tremors, hair LOSS, trouble sleeping, infxn, numbness/tingling, hyperkalemia, abnormal kidney fxn
Cyclosporine is also known as Sandimmune
Main side effects of cyclosporine include HA, tremor, abnormal kidney fxn, HTN, high BG, high cholesterol, infxn, hyperkalemia, excessive hair GROWTH, trouble sleeping, overgrowth gums
Prednisone is also known as Deltasone
True or false: prednisone dose might be lowered if you remain rejection free post-tx True
Main side effects of prednisone include High BG, wt gain, hunger, puffy cheeks, infxn, acne, bruising, osteoporosis, high cholesterol, mood swings, night sweats, anxiety, stomach upset, blurry vision (cataracts)
Mycophenolate mofetil is also known as CellCept, MMF, MPA, RS
True or false: mycophenolate mofetil is a prodrug of mycophenolic acid True
Mycophenolate mofetil is a inhibitor of Inosine monophosphate dehydrogenase (IMPDH), an enzyme. This affects a pathway in B/T lymphocytes
Mycophenolate mofetil (MMF) can lower your WBCs as well as Platelets
Main side effects of MMF include Heartburn, stomach upset, infxn, N/V/D, neutropenia, thrombocytopenia
What is Imuran also called? Azathioprine
Azathioprine can lower your __ and __ WBC, PLT
What other common med should you be cautious of combining with azathioprine? Allopurinol
Main SE of azathioprine include N/V, infxn, neutropenia, thrombocytopenia
Antithymocyte globulin (Atgam, Thymoglobulin) is given for what reason? To prevent or treat acute rejection
Antithymocyte globulin can only be given in what route? IV
Main SE of antithymocyte globulin include Difficulty breathing, N/V/D, fever, chills, rash, muscle aches, infxn, pain during infusion
OKT3's purpose is Given to treat rejection
OKT3 can only be given IV
Precautions with OKT3 include Wheezing, SOB, dysphagia, rapid HR, rash, itching.
True or false: most pt. do not have adverse rxn to OKT3 in first 3 doses False. Common to have mild adverse reactions
Main SE of OKT3 include Wheezing, difficulty breathing, CP, fever, chills, N/V/D, tremor, HA, infxn, fast HR, muscle stiffness
Daclizumab/Basiliximab is a medication that suppresses immune system amd is given in what route at what time? IV, at time of tx and 2x more days 4 and 14
Created by: lapio