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Tx Rx List
Term | Definition |
---|---|
Tacrolimus is also known as | Prograf, FK506 |
Tacrolimus is a ___ type medication | Anti-rejection, macrolide antibiotic with immunosupressive properties |
Main side effects of tacrolimus include | Headaches, HTN, N/D, high BG, tremors, hair LOSS, trouble sleeping, infxn, numbness/tingling, hyperkalemia, abnormal kidney fxn |
Cyclosporine is also known as | Sandimmune |
Main side effects of cyclosporine include | HA, tremor, abnormal kidney fxn, HTN, high BG, high cholesterol, infxn, hyperkalemia, excessive hair GROWTH, trouble sleeping, overgrowth gums |
Prednisone is also known as | Deltasone |
True or false: prednisone dose might be lowered if you remain rejection free post-tx | True |
Main side effects of prednisone include | High BG, wt gain, hunger, puffy cheeks, infxn, acne, bruising, osteoporosis, high cholesterol, mood swings, night sweats, anxiety, stomach upset, blurry vision (cataracts) |
Mycophenolate mofetil is also known as | CellCept, MMF, MPA, RS |
True or false: mycophenolate mofetil is a prodrug of mycophenolic acid | True |
Mycophenolate mofetil is a inhibitor of | Inosine monophosphate dehydrogenase (IMPDH), an enzyme. This affects a pathway in B/T lymphocytes |
Mycophenolate mofetil (MMF) can lower your WBCs as well as | Platelets |
Main side effects of MMF include | Heartburn, stomach upset, infxn, N/V/D, neutropenia, thrombocytopenia |
What is Imuran also called? | Azathioprine |
Azathioprine can lower your __ and __ | WBC, PLT |
What other common med should you be cautious of combining with azathioprine? | Allopurinol |
Main SE of azathioprine include | N/V, infxn, neutropenia, thrombocytopenia |
Antithymocyte globulin (Atgam, Thymoglobulin) is given for what reason? | To prevent or treat acute rejection |
Antithymocyte globulin can only be given in what route? | IV |
Main SE of antithymocyte globulin include | Difficulty breathing, N/V/D, fever, chills, rash, muscle aches, infxn, pain during infusion |
OKT3's purpose is | Given to treat rejection |
OKT3 can only be given | IV |
Precautions with OKT3 include | Wheezing, SOB, dysphagia, rapid HR, rash, itching. |
True or false: most pt. do not have adverse rxn to OKT3 in first 3 doses | False. Common to have mild adverse reactions |
Main SE of OKT3 include | Wheezing, difficulty breathing, CP, fever, chills, N/V/D, tremor, HA, infxn, fast HR, muscle stiffness |
Daclizumab/Basiliximab is a medication that suppresses immune system amd is given in what route at what time? | IV, at time of tx and 2x more days 4 and 14 |