patho exam 1
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| What is a stressor? | any factor that disturbs homeostasis, producing stress
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| What is homeostasis? | maintenance of a constant stable environment within the body
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| what is alllostasis? | Is the process of achieving stability, or homeostasis, through physiological or behavioral change
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| What did Hans Seyle look at when looking at stress? | only looked at physiological stressors
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| What are the three GAS stages of stress? | Alarm, action, exhaustion
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| what does the first stage of stress involve? | CNS-CRH (hypothalamus) response
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| what does the second stage of stress involve? | Entire neuroendocrine response (if successful recovery)
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| what does the third stage of stress involve? | Progressive breakdown of compensatory responses
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| when does a stress response occur? | when demands greater than person’s ability to cope
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| what does Endogenous mean? | inside body
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| what does Exogenous mean? | outside body, environmental
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| what are the organs involved in the HPA axis? | hypothalamus, anterior pituitary, adrenal glands
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| What are the hormones involved in the HPA axis? | Corticotropin releasing hormone (released by hypothalamus); ACTH (secreted by anterior pituitary); cortisol (secreted by adrenal gland)
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| what is the inflammatory/immune shift? | Increase in cortisol/NE/Epi causes a DECREASE in Th1 cells while at the same time an INCREASE in Th2 cells
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| what do Th1 cells do? | Promote cellular immunity to protect the body from intracellular antigens
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| what do Th2 cells do? | Produce antibodies that protect the body from extracellular antigens
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| What does Th1 secrete? | IL-2, IL-12, TNFa, INF-y
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