EMT NAIT Pharmacology, nervous system
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Sympathetic Division | Responsible for Fight or Flight reactions
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Sympathetic Division- heart | 2 Increased heart rate (Beta 1 receptors)
Increased force of contraction (beta 1 receptors)
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Sympathetic Division- blood vessels | Constricts abdominal blood vessels (Alpha 1)
Constricts peripheral blood fessels (Alpha 1)
Dilates muscular blood vessels (beta 2)
Constricts muscular blood vessels (Alpha 1)
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Sympathetic Division- Lungs | Dilates bronchi (beta 2)
Skeletal Muscles- breakdown of glycogen to glucose (beta 2)
Metabolism (increase of up to 100%) Alpha 1
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Sympathetic Division- Glands | Adrenal Glands- release epinephrine and norepinephrine (cholinergic receptors)
Salivary glands (constricts vessels, thick viscous secretions) (alpha 1$2)
gastric, Pancreas- inhibits (alpha 1&2)
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Sympathetic Division- Sweat glands | merocrine glands- copious watery secretrion
apocrine glands- thick organic secretions (both by cholinergic receptors)
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Sympathetic Division- Gallbladder and bile | relaxation (beta 2)
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Sympathetic Division- Urinary bladder | wall- relaxation (beta 2)
sphincter- contraction (Alpha 1)
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Sympathetic Division- eyes | Ciliary muscle- relax for far vision (beta)
Pupil- Dilation-radial fibers (alpha 1)
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Sympathetic Division - Arrector pilli | (makes your hair stand up) (Alpha 1)
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Sympathetic Division- Blood | Blood- Increase coagulation (Alpha 2)
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Sympathetic Division- sex organs | Ejaculation (Alpha 1)
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Parasympathetic- Heart | Slowed HR (alpha 2)
Coronary artery dilation (Alpha 2)
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Parasympathetic- blood vessels | blood vessels- no effect
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Parasympathetic- Lungs | Bronchoconstricion (cholinergic receptors, small effect of Alpha 1)
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Parasympathetic- glands | Adrenal- no effect
Salivary- dilation of vessels and thin copious secretions- Cholinergic receptors
Gastric, pancreas- stimulation (cholinergic receptors
Lacrimal glands- secretion (cholinergic receptors)
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Parasympathetic- Sweat | no effect
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Parasympathetic- Gut | Increased motility
Decreased tone (cholinergic receptors)
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Parasympathetic- Gallbladder and bile | Contraction (cholinergic receptors)
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Parasympathetic- Urinary bladder | wall- contraction
sphincter- relaxation (cholinergic receptors)
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Parasympathetic- Eye | Ciliary muscle- Contraction for near vision
Pupil- Constriction (cholinergic receptors)
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Parasympathetic- arrector pili | no effect
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Parasympathetic- blood | no effect
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Parasympathetic- sex organs | Erection
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Parasympathetic Division | Rest and Digest
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Agonists | Drugs that interact with a receptor to stimulate a response
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Antagonist | Drugs that attach to a receptor to prevent a response
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Partial Agonist | Drugs that interact with a receptor to stimulate a response but inhibit other responses
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Salbutamol- Bronchodilator | stimulates Beta 2 to relax bronchi and vascular smooth muscle
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Glucagon- hyperglycemic agent | beta 2 agonist- stimulates glycogenolysis (liver stores of glycogen turn to glucose for use in the blood stream)
relaxes musculature of GI tract
positive inotropic and chronotropic effects
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Epinephrine- sympathomimetic, adrenergic | directly stimulates alpha and beta adrenergic receptors
Bronchodilation- beta 2
+chronotropic&inotropic - beta1
Vasodilation- beta 2
Vasoconstriction- Alpha 1
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Chronotropic | +/- rate of contraction (heart)
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Inotropic | +/- force of contraction (heart)
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