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EMT NAIT Pharmacology, nervous system

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Term
Definition
Sympathetic Division   Responsible for Fight or Flight reactions  
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Sympathetic Division- heart   2 Increased heart rate (Beta 1 receptors) Increased force of contraction (beta 1 receptors)  
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Sympathetic Division- blood vessels   Constricts abdominal blood vessels (Alpha 1) Constricts peripheral blood fessels (Alpha 1) Dilates muscular blood vessels (beta 2) Constricts muscular blood vessels (Alpha 1)  
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Sympathetic Division- Lungs   Dilates bronchi (beta 2) Skeletal Muscles- breakdown of glycogen to glucose (beta 2) Metabolism (increase of up to 100%) Alpha 1  
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Sympathetic Division- Glands   Adrenal Glands- release epinephrine and norepinephrine (cholinergic receptors) Salivary glands (constricts vessels, thick viscous secretions) (alpha 1$2) gastric, Pancreas- inhibits (alpha 1&2)  
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Sympathetic Division- Sweat glands   merocrine glands- copious watery secretrion apocrine glands- thick organic secretions (both by cholinergic receptors)  
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Sympathetic Division- Gallbladder and bile   relaxation (beta 2)  
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Sympathetic Division- Urinary bladder   wall- relaxation (beta 2) sphincter- contraction (Alpha 1)  
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Sympathetic Division- eyes   Ciliary muscle- relax for far vision (beta) Pupil- Dilation-radial fibers (alpha 1)  
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Sympathetic Division - Arrector pilli   (makes your hair stand up) (Alpha 1)  
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Sympathetic Division- Blood   Blood- Increase coagulation (Alpha 2)  
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Sympathetic Division- sex organs   Ejaculation (Alpha 1)  
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Parasympathetic- Heart   Slowed HR (alpha 2) Coronary artery dilation (Alpha 2)  
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Parasympathetic- blood vessels   blood vessels- no effect  
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Parasympathetic- Lungs   Bronchoconstricion (cholinergic receptors, small effect of Alpha 1)  
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Parasympathetic- glands   Adrenal- no effect Salivary- dilation of vessels and thin copious secretions- Cholinergic receptors Gastric, pancreas- stimulation (cholinergic receptors Lacrimal glands- secretion (cholinergic receptors)  
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Parasympathetic- Sweat   no effect  
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Parasympathetic- Gut   Increased motility Decreased tone (cholinergic receptors)  
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Parasympathetic- Gallbladder and bile   Contraction (cholinergic receptors)  
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Parasympathetic- Urinary bladder   wall- contraction sphincter- relaxation (cholinergic receptors)  
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Parasympathetic- Eye   Ciliary muscle- Contraction for near vision Pupil- Constriction (cholinergic receptors)  
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Parasympathetic- arrector pili   no effect  
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Parasympathetic- blood   no effect  
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Parasympathetic- sex organs   Erection  
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Parasympathetic Division   Rest and Digest  
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Agonists   Drugs that interact with a receptor to stimulate a response  
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Antagonist   Drugs that attach to a receptor to prevent a response  
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Partial Agonist   Drugs that interact with a receptor to stimulate a response but inhibit other responses  
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Salbutamol- Bronchodilator   stimulates Beta 2 to relax bronchi and vascular smooth muscle  
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Glucagon- hyperglycemic agent   beta 2 agonist- stimulates glycogenolysis (liver stores of glycogen turn to glucose for use in the blood stream) relaxes musculature of GI tract positive inotropic and chronotropic effects  
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Epinephrine- sympathomimetic, adrenergic   directly stimulates alpha and beta adrenergic receptors Bronchodilation- beta 2 +chronotropic&inotropic - beta1 Vasodilation- beta 2 Vasoconstriction- Alpha 1  
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Chronotropic   +/- rate of contraction (heart)  
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Inotropic   +/- force of contraction (heart)  
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Created by: staggeringduck
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