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EMT Pharmacology

EMT NAIT Pharmacology, nervous system

Sympathetic Division Responsible for Fight or Flight reactions
Sympathetic Division- heart 2 Increased heart rate (Beta 1 receptors) Increased force of contraction (beta 1 receptors)
Sympathetic Division- blood vessels Constricts abdominal blood vessels (Alpha 1) Constricts peripheral blood fessels (Alpha 1) Dilates muscular blood vessels (beta 2) Constricts muscular blood vessels (Alpha 1)
Sympathetic Division- Lungs Dilates bronchi (beta 2) Skeletal Muscles- breakdown of glycogen to glucose (beta 2) Metabolism (increase of up to 100%) Alpha 1
Sympathetic Division- Glands Adrenal Glands- release epinephrine and norepinephrine (cholinergic receptors) Salivary glands (constricts vessels, thick viscous secretions) (alpha 1$2) gastric, Pancreas- inhibits (alpha 1&2)
Sympathetic Division- Sweat glands merocrine glands- copious watery secretrion apocrine glands- thick organic secretions (both by cholinergic receptors)
Sympathetic Division- Gallbladder and bile relaxation (beta 2)
Sympathetic Division- Urinary bladder wall- relaxation (beta 2) sphincter- contraction (Alpha 1)
Sympathetic Division- eyes Ciliary muscle- relax for far vision (beta) Pupil- Dilation-radial fibers (alpha 1)
Sympathetic Division - Arrector pilli (makes your hair stand up) (Alpha 1)
Sympathetic Division- Blood Blood- Increase coagulation (Alpha 2)
Sympathetic Division- sex organs Ejaculation (Alpha 1)
Parasympathetic- Heart Slowed HR (alpha 2) Coronary artery dilation (Alpha 2)
Parasympathetic- blood vessels blood vessels- no effect
Parasympathetic- Lungs Bronchoconstricion (cholinergic receptors, small effect of Alpha 1)
Parasympathetic- glands Adrenal- no effect Salivary- dilation of vessels and thin copious secretions- Cholinergic receptors Gastric, pancreas- stimulation (cholinergic receptors Lacrimal glands- secretion (cholinergic receptors)
Parasympathetic- Sweat no effect
Parasympathetic- Gut Increased motility Decreased tone (cholinergic receptors)
Parasympathetic- Gallbladder and bile Contraction (cholinergic receptors)
Parasympathetic- Urinary bladder wall- contraction sphincter- relaxation (cholinergic receptors)
Parasympathetic- Eye Ciliary muscle- Contraction for near vision Pupil- Constriction (cholinergic receptors)
Parasympathetic- arrector pili no effect
Parasympathetic- blood no effect
Parasympathetic- sex organs Erection
Parasympathetic Division Rest and Digest
Agonists Drugs that interact with a receptor to stimulate a response
Antagonist Drugs that attach to a receptor to prevent a response
Partial Agonist Drugs that interact with a receptor to stimulate a response but inhibit other responses
Salbutamol- Bronchodilator stimulates Beta 2 to relax bronchi and vascular smooth muscle
Glucagon- hyperglycemic agent beta 2 agonist- stimulates glycogenolysis (liver stores of glycogen turn to glucose for use in the blood stream) relaxes musculature of GI tract positive inotropic and chronotropic effects
Epinephrine- sympathomimetic, adrenergic directly stimulates alpha and beta adrenergic receptors Bronchodilation- beta 2 +chronotropic&inotropic - beta1 Vasodilation- beta 2 Vasoconstriction- Alpha 1
Chronotropic +/- rate of contraction (heart)
Inotropic +/- force of contraction (heart)
Created by: staggeringduck