First Aid Biochemistry USMLE
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| show | PKU
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| show | NADH increase prevents gluconeogenesis by shunting pyruvate and oxaloacetate to lactate and malate
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| 2 year old girl has increase in abdominal girth, failure to thrive and skin and hair depigmentation - what is the diagnosis | show 🗑
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| show | B3 (pellagra)
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| show | Gilberts syndrome
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| show | Alkaptonuria
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| show | Familial hypercholesterolemia, lDL receptor
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| Condensed by negatively charged DNA looped twice around positively charged H2a, H2b, H3 and H4 histones (nucleosome bead) | show 🗑
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| show | H1 histone
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| show | Heterochromatin
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| Less condensed, transcriptionally active chromatin | show 🗑
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| Name purines | show 🗑
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| show | C, T, UCUT Pye
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| show | Purines
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| show | Pyrimidines
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| Which nucleotide has a ketone | show 🗑
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| Which nucleotide has methyl | show 🗑
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| Deamination of cytosine makes _ | show 🗑
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| Uracil is found in _ Thymine is found in _ | show 🗑
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| show | GC (3 H bonds), AT is weaker (2 H bonds)
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| show | Increases
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| Nucleotides are linked by _ | show 🗑
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| show | TransItion (identical)
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| show | TransVersion (conVersion between types)
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| 4 features of genetic code | show 🗑
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| Name type of mutation - same amino acid, often base change in 3d position of codon tRNA wobble) | show 🗑
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| show | Missence mutation
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| show | Nonsense mutation
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| Name type of mutation - change resulting in misreading of all nucleotides downstream, usually resulting in a truncated protein | show 🗑
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| show | Single origin of replication - continuous DNA synthesis on leading strand and discontinuous (okazaki fragments) on lagging strand
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| show | Primase makes RNA PRIMER on which DNA polymerase III can initiate replication
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| Elongates the chain by adding deoxynucleotides to the 3 end until it reaches primer of preceding fragment | show 🗑
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| Name enzyme that degrades RNA primer | show 🗑
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| Has 5'-3' synthesis and proofreads with 3'-5' exonuclease | show 🗑
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| show | DNA topoisomerases
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| show | Xeroderma pigmentosum (skin sensitivity to UV light)Ataxia-telangiectasia (x rays)Blooms syndrome (radiation)Fanconis anemia (cross linking agents)
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| Defective excision repair such as uvr ABC endonuclease. Results in inability to repair thymidine dimers, which form in DNA when exposed to UV light. Associated with dry skin and with melanoma and other cancersInheritance pattern | show 🗑
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| show | 5'-->3'
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Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
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To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
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