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First Aid Biochemistry USMLE

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show PKU  
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show NADH increase prevents gluconeogenesis by shunting pyruvate and oxaloacetate to lactate and malate  
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2 year old girl has increase in abdominal girth, failure to thrive and skin and hair depigmentation - what is the diagnosis   show
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Alcoholic develops rash, diarrhea and altered mental statusWhat is the vitamin defficiency   show
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show Gilberts syndrome  
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51 year old man has black spots on his sclera and has noted that urine turns black when he is standing   show
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25 year old complains of chest pains and has xanthoma of Achilles tendonWhat is his disease and where is the defect   show
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show Chromatin  
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show H1 histone  
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show Heterochromatin  
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show Euchromatin  
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Name purines   show
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show C, T, UCUT Pye  
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show Purines  
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show Pyrimidines  
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show guanine  
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show thymine  
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Deamination of cytosine makes _   show
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Uracil is found in _ Thymine is found in _   show
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Which bond is stronger GC or AT   show
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If GC content is increased what happens to melting temperature   show
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show 3-5 phosphodiesterase bond  
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Substituting purine for purine or pyrimidine for pyrimidine is called ?   show
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Substituting purine for pyrimidine or vice versa   show
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4 features of genetic code   show
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Name type of mutation - same amino acid, often base change in 3d position of codon tRNA wobble)   show
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Name type of mutation - changed amino acid (conservative - new amino acid is similar in chemical structure)   show
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show Nonsense mutation  
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show Frameshift mutation  
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show Single origin of replication - continuous DNA synthesis on leading strand and discontinuous (okazaki fragments) on lagging strand  
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show Primase makes RNA PRIMER on which DNA polymerase III can initiate replication  
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Elongates the chain by adding deoxynucleotides to the 3 end until it reaches primer of preceding fragment   show
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show 5'-3' exonuclease activity of DNA polymerase I  
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Has 5'-3' synthesis and proofreads with 3'-5' exonuclease   show
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show DNA topoisomerases  
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show Xeroderma pigmentosum (skin sensitivity to UV light)Ataxia-telangiectasia (x rays)Blooms syndrome (radiation)Fanconis anemia (cross linking agents)  
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show Xeroderma pigmentosumAutosomal recessive  
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In which direction is Dna and RNA synthesized   show
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