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Advanced Patho EXAM 3

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Question
Answer
List 3 primary skin lesions.   Macule, papule and nodule  
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Describe a macule and give an example.   spot, circumscribed, up to 1cm; i.e. cafe au lait, mongolian spots  
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Describe a papule and give an example.   bump, palpable, <5mm in diameter; i.e. mole  
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Describe a nodule and give an example.   like a papule but diameter=5mm to 2 cm; i.e. xanthoma  
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What is atopic dermatitis (eczema) and how does it occur/who is at risk?   an itchy, inflammatory skin d/o with defined erythema with edema, vesicles and weeping at the acute stage and lichenification in the chronic stage; difficult to identify causative agent. High occurrence in kids less than 5 yrs  
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Describe the skin.   has 2 layers: an outer epidermis and inner dermis, separated by a basement membrane  
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What is name of the major cell of the epidermis?   keratinocytes  
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What cells give the skin its color?   melanocytes; they release melanin.  
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What cells in the epidermis are responsible for its re-population?   langerhans cells  
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True or false, the dermis is the connective tissue layer that JOINS the epidermis and SQ fat layer.   False, it SEPARATES  
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What is lichenification?   thickened, leathery and roughened skin characterized by prominent markers; caused by repeated rubbing and scratching  
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Define xerosis.   dry skin  
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Definition: Skin d/o characterized by papules and plaques with silvery scale; unknown cause; can appear anywhere but popular spots include knees, elbows, lower back and scalp.   what is psoriasis  
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Definition: A group of related diseases characterized by bullous eruptions, thought to be autoimmune reactions.   what is pemphigus  
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What are the s/s of pemphigus?   blisters on the skin and mucous membranes  
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What is "Rhus" dermatitis and what s/s does it produce?   an allergy to plants, i.e. poison ivy, poison oak, etc. s/s appear within 24 hrs of contact; pruritis, erythema, vesicle formation  
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What is the best line of treatment for eczema?   moisturizes and/or steroids  
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When assessing a melanoma, what acronym is used and what does it stand for?   A, B, C, D Asymmetry border color diameter  
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What are the risk factors to skin cancer?   smoking and sun exposure  
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What is the difference between basal cell carcinoma and melanoma?   melanoma can be deadly; basal cell carcinoma are common growths that are mostly benign, pearly like appearance  
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The skin cancer that arises from keratinocytes due skin exposure to light is known as _____________   squamous cell carcinomas  
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A pigment disorder of the skin is known as?   vitiligo aka leukoderma  
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What is the treatment for verrucae?   aka warts; liquid nitrogen, cryotherapy and/or laser removal  
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What is the difference between Herpes simplex virus 1 and HSV 2?   HSV1= above the waist (i.e. cold sore) HSV2= below the waist (i.e. genital warts)  
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How are fungal infections named?   Tinea____________ location i.e. tinea capititis  
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What is the cause of impetigo?   it is a bacterial infection caused by staph or strep  
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What happens if Syphillis is left untreated?   if it goes to the 3rd stage, there can be cardiac involvement  
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What skin d/o has a characteristic butterfly rash on the face?   lupus erythematosus  
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True or false, seborrheic dermatitis can be cured.   False, it can not be cured but is treatable  
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A self-limiting skin disorder, characterized by shiny, white topped, purplish, polygonal papules on the wrist, ankles and trunk.   lichen planus  
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What rash is seen in young persons, highest in spring and fall and its initial lesion is a herald patch on the neck or trunk?   pityriasis rosea aka the christmas tree rash  
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Common in children, this infection is from bacteria that live in the top layers of the skin. Appears as red sores that turn into blisters, ooze, then crust over.   impetigo  
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Why is it important to promptly treat lime disease?   there are 3 stages and stage 2 can cause peripheral neuropathy, meningitis and involve the cardiac system; stage 3 can cause oligoarticular arthritis  
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What does Group A Beta Hemolytic strep cause?   scarlet fever  
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What are the s/s of erythema multiforme?   Target lesions caused by the centrifugal spread of red maculopapules with a purpuric, vesicular, or papular center. Mainly on hands, feet, and extensor surface of forearms and legs  
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A blister >5mm is known as what?   bulla i.e. pemphigus  
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The characteristics of a mosquito bite are an example of what?   a wheal  
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A small blister up to 5mm (i.e. herpes) is known as what type of skin lesion?   vesicle  
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A lesion that can be benign or malignant and felt as a nodule is known as ________?   a tumor  
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An acute localized inflammatory disease of dermatomal segment is known as?   shingles  
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True or false, basal cell carcinoma metastasize.   False, they do not.  
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