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Pulmonary and Acid Base Pathophysiology

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Term
Definition
respiration is   the cellular process that uses oxygen to make ATP  
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respiration rate in this class is equal to   ventilation rate  
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the ventilation rate is   the number of times gas is exchanged in a minute  
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ventilation is   the movement of air in and out of the lungs  
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breathing allows   absorption of oxygen and elimination of carbon dioxide  
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tissue respiration is   gas exchange between blood and tissues  
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the five stages of pulmonary system development   embryotic phase, pseudogladnular phase, canalicular phase, terminal sac phase, alveolar phase  
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the embryonic phase occurs from   3-7 weeks  
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the pseudogladular phase occurs from   7-16 weeks  
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the canalicular phase occurs from   16-24 weeks  
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the terminal sac phase occurs from   24-36 weeks  
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the alveolar phase occurs from   36 weeks to term/adult usually until 3 years  
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The diaphram is formed during the   pseudoglandular phase around the 8th-10th week  
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During the embryonic phase   the trachea divides into right and left  
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During the pseurogladular phase   there is continued differentiation of bronchi and 25,000 terminal bronchioles start splitting into 23 parts, diaphram is formed and distal airways start to be formed in the later weeks  
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During the canalicular phase   maturation of the pulmonary alveoli begins, pulmonary surfactant starts to be produced, blood flow begins  
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Terminal sac phase   start to get grape like structures  
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Alveolar phase   start to mature and and develop and differentiation of more mature alveoli takes place up to three years of life.  
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The pulmonary system develops in this direction   caudaly  
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Pulmonary Surfactant is produced by   Type II pneumocyte cells  
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Alveoli are made of   Type I pneumocyte cells  
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The pulmonary system develops from this   the primitive foregut endoderm  
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Gas exchange occurs in this   the pulmonary acinus  
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The pulmonary acinus is made up of these four items   bronchioles, alveolar ducts, alveolar sacs and alveoli  
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The pulmonary acinus allows this   Oxygen to enter circulation and the carbon dioxide is diffused from circulation  
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Pulmonary Circulation does these four things   facilitates gas exchange, delivers nutrients to lung tissues, acts as a reservoir for the LV, serves as a filter  
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The bronchial arteries do this   provide a small amount of oxygenated blood to lung tissues  
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the pulmonary arteries do this   provide deoxygenated blood  
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compared to systemic circulation, pulmonary circulation   has lower pressures and lower amounts of resistance compared to systemic circulation  
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this many vessels are profused at a time   one third  
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the pulmonary artery is exposed to this much pressure   1/5 the pressure in comparison to systemic vessels  
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the pulmonary artery has this amount of walls   thinner walls compared to others in circulation  
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When the right ventricles output increases   more blood is delivered to the lungs and become oxygenated  
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when excess fluid volume occurs or LV dysfunction occurs   there is an increase in hydrostatic pressure which can allow for storage in the pulmonary vessels  
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if there is no room for storage in pulmonary vessels the fluid builds up in   the interstitial spaces  
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The primary function of the pulmonary system is to   exchange gases from environmental air to the blood stream  
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The exchange of gases from the environmental air to the bloodstream is done by   ventilation, diffusion and perfusion  
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diffusion is   the movement of gases between air spaces in lungs and blood stream  
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Perfusion is driven by   cardiac output and is a primary role of the cardiovascular system.  
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breathing is   inspiration and exhalation  
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4 brain centers control breathing   brain stem, cerebral cortex, chemoreceptors and mechanoreceptors  
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the chemoreceptors are located in   the peripheral arteries  
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mechanoreceptors can sense   breathing patterns  
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the medullary respiratory center consists of   the inspiratory center and the expiratory center  
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the inspiratory center is also known as the   dorsal respiratory group  
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the inspiratory center or dorsal respiratory group controls   basic rhythm of breathing  
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the inspiratory center receives input from   cranial nerves 9 and 10 and the chemoreceptors  
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the inspiratory center sends output to   the diaphram  
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the expiratory center is also known as   the ventral respiratory group  
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the expiratory center is activated during this   physical activity  
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normal expiration is a   passive process  
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the regular normal breathing center is the   inspiratory or dorsal group  
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The dorsal respiratory center receives afferent impulses from   peripheral chemo receptors that are located in the carotid and aortic bodies  
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chemoreceptors can detect the   CO and Oxygen levels  
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cranial nerves 9 and 10 are   Glossopharangeal and vagus nerve  
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the pneumotaxic center is located in the   upper pons  
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the function of the pneumotaxic center is that it   turns off inspiration and limits bursts of action potentials in phrenic nerve  
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the pneumotaxic center does this to tidal volume and this to the respiratory rate   limits tidal volume and increases respiratory rate  
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the pneumotaxic center antaganizes this center   the apeneustic center  
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the apeneustic center is located in   the lower pons  
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stimulation of apeneustic center excites the   inspiratory center in the medulla  
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apeneustic center controls the intensity of breathing by   prolonging action potentials of the phrenic nerve and prolonging the contraction of the diaphram  
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apneusis is   an abnormal breathing pattern with prolonged inspiratory gasps and a brief expiratory movement  
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apnic individuals are those who have one of the following   severe neurological damage, decerebrate posture, fixed or dialated pupils, coma, profound stupor, quadraparesis, absent corneal reflex, dolls eye, negative oculocephalic reflex  
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apnic individuals are those who have one of the following   severe neurological damage, decerebrate posture, fixed or dialated pupils, coma, profound stupor, quadraparesis, absent corneal reflex, dolls eye, negative oculocephalic reflex  
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the cerebral cortex temporarily overrides   automatic brain stem centers  
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automatic brain stem centers include   limbic system and hypothalamus  
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the automatic brain stem centers help to regulate   memory  
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hypothalamus regulates this part of memory   psychosomatic and emotions associated with anxiety  
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hyperventilation   increases the volume and frequency of breath  
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people who are hyperventilating are   hypocapnic with low PaCO2  
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low PaCO2 correlates with   respiratory alkalosis  
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chemoreceptors are located three places   centrally, medulliarily and peripherally  
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central chemoreceptors are responsible for   minute to minute control of breathing  
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central chemoreceptors are sensitive to   changes in pH of the CSF  
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low pH is indicative of   hyperventilation  
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high pH is indicative of   hypoventilation  
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high PaCO2 is related to this pH   low  
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peripheral chemoreceptors are located in   aortic bodies in the aortic arch  
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