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CRNI Pharmacology

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Natural Penicillin
Penicillin G, Gram +, -cidal
Penicillinase-resistant   Staphcillin,Unipen, ^liver enzymes, Staph Aureus/Epidermis,  
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Aminopenicillins   Gram -, not for penicillinase  
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Ampicillin Sodium (Omnipen N)   most unstable, 4 hrs in D5W, 8 in 0.9%  
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1st Gen Cephalosporin   Cefazolin Sodium (Kefzol) Gram +, nephotoxic  
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2nd Gen Cephalosporin   Mefoxin,Cefotan, Gram -, bleed, diarrhea, N, Colitis  
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3rd Gen Cephalosporin   Gram -, crosses blood-brain barrier, ROCEPHIN, meningitis, bacteremia, septicemia, resp, genito, Lyme  
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Tetracyclines   static-> cidal, broad spectrum, VIBRAMYCIN IV/Doxycycline Hytrate, sub for Penicillin  
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Aminoglycosides   cidal, Gram -, Gentamycin, Amikacin, Tobramycin, nephrotoxic, Ototoxic, P & T  
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Erythromycin   Gram -+, static->cidal, ERYTHROCIN IV, sub for penicillin, hearing loss & phlebitis!  
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Clindamycin Phosphate   CLEOCIN PHOSPHATE, static, aer+anaer, sub for penicillin, diarrhea, fatal colitis, hypot,cardio-pulm arrest  
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Vancomycin HCL   VANCOCIN,cidal, MRSA, nephrotoxic/ototoxic,over 60 min, "redman syndrome"  
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