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CRNI Pharmacology

Natural PenicillinPenicillin G, Gram +, -cidal
Penicillinase-resistant Staphcillin,Unipen, ^liver enzymes, Staph Aureus/Epidermis,
Aminopenicillins Gram -, not for penicillinase
Ampicillin Sodium (Omnipen N) most unstable, 4 hrs in D5W, 8 in 0.9%
1st Gen Cephalosporin Cefazolin Sodium (Kefzol) Gram +, nephotoxic
2nd Gen Cephalosporin Mefoxin,Cefotan, Gram -, bleed, diarrhea, N, Colitis
3rd Gen Cephalosporin Gram -, crosses blood-brain barrier, ROCEPHIN, meningitis, bacteremia, septicemia, resp, genito, Lyme
Tetracyclines static-> cidal, broad spectrum, VIBRAMYCIN IV/Doxycycline Hytrate, sub for Penicillin
Aminoglycosides cidal, Gram -, Gentamycin, Amikacin, Tobramycin, nephrotoxic, Ototoxic, P & T
Erythromycin Gram -+, static->cidal, ERYTHROCIN IV, sub for penicillin, hearing loss & phlebitis!
Clindamycin Phosphate CLEOCIN PHOSPHATE, static, aer+anaer, sub for penicillin, diarrhea, fatal colitis, hypot,cardio-pulm arrest
Vancomycin HCL VANCOCIN,cidal, MRSA, nephrotoxic/ototoxic,over 60 min, "redman syndrome"
Created by: ALomibao87