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Acquired Immonodeficiency Syndrome

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Question
Answer
What is a retrovirus?   have the enzyme reverse transcriptase-synthesizes DNA from an RNA template,a reverse transcription  
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What is so unusual about the reverse transcriptase?   enzyme can replicate a double strand of DNA from a single strand of RNA  
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What is the receptor for HIV attachment to cells, and what cells have this receptor?   HIV attaches to the T cell receptor in CD4 or Th cells  
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Discuss the transmission of HIV   infection requires access to recipient's bloodstream via cut or tear in skin-which is exposed to semen, vaginal fluids, or blood  
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When do overt symptoms of AIDS appear?   8-10 yrs after initial infection with HIV or when CD4 cell count drops to less than 200cells/mm  
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How does the genome of HIV persist in certain human cells?   genome of HIV persists in certain human cells because reverse transcriptase makes DNA ccopy-intigrates to become part of cell genome  
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What actually kills AIDS patients?   CD4 cells gradually reduced to zero-prevents formation of memory cells-expanded cell population of any immune cells--opportunistic infections can't be surmounted by immune system  
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what is the relationship between AIDS and Kaposi's sarcoma   high incidence of Kaposi's sarcoma in AIDS pts due to reactivation of the human herpes virus 8  
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How can the spread of AiDS be reduced?   if people avoid anal sex, do not have multiple sex partners, avoid recapping needles, use condoms, abstinence, single sex partner, use gloves/proper face/eye covering if mucous membrane exposure possible  
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