1st Semester Drugs
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| Albuterol Drug Class | Bronchodialator
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| Albuterol MOA | Selective Beta 2 antagonist which stimulates adrenergic receptors of the sympthomimetic nervous system, resulting in smooth muscle relaxation
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| Albuterol Indications | Respiratory distress, treatment of bronchospasm in pts with COPD
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| Albuterol Contraindications | Cardiac insufficiency, hypersensitivity
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| Albuterol Adverse Reactions | Restlessness, tremors, dizziness, palpations, tachycardia, nervousness, peripheral vasodialation, nausea, vomiting, hyperglycemia, increased BP, paradoxial bronchospasm
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| Albuterol How it's supplied | 2,5mG/3mL vial inhalation solution
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| Albuterol Adult Dosage/Administration | 2.5, may give more NPR nebulizer
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| Albuterol Ped Dosage/Administration | >18 mths 2.5 Nebulizer
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| Albuterol Onset | 5-15 min
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| Albuterol Peak Effect | 60-90 min
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| Albuterol Duration | 3-6 hours
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| Calcium Chloride Drug Class | Electrolyte
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| Calcium Chloride MOA | Increases cardiac contractile state
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| Calcium Chloride Indications | Calcium channel blocker toxicity, hypocalcemia when prompt increase in calcium plasma is required, combat hyperkalemia as the precipitant to cardiac arrest
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| Calcium Chloride Contraindications | V Fib arrest, digitalis toxicity
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| Calcium chloride Adverse Reactions | tingling sensations, calcium taste, "heat wave", peripheral dialation, burning sensation, moderate drop in BP
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| Calcium chloride supplied | 1Gm/10mL prefilled syringe
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| Calcium chloride dosage/administration Adult | Cardiac arrest, Evidence of ESRD w/ suspected hyperkalemia 1Gm
SVT-1Gm over 5 min
A Fib/Flutter 1Gm over 5 min
OD- 20 mg/kg
Slow IV/IO push
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| Calcium chloride Ped dosage/administration | 20mg/kg Slow IV/IO push
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| Calcium chloride onset | 3-5 min
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| calcium chloride peak effect | 5-15 min
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| calcium chloride duration | 4 hrs
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| Adenosine Class | Endogenous nucleoside
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| Adenosine MOA | slows conduction through AV node, interuption of reentry pathway through AV node, restores normal Sinus rhythm in pt with PSVT
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| Adenosine indications | conversion to NSR of PSVT, including that associated with accessory bypass tracts, conversion of wide complex Tachycardia of unknown origin
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| Adenosine contraindications | 2nd or 3rd degree heart block, sick sinus syndrome, hypersensitivity
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| Adenosine adverse reactions | sense of impending doom, flushing, chest pressure, throat tightness, numbness, brief period of asystole
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| Adenosine how its supplied | 6mg/2mL vial (3mg/mL)
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| Adenosine adult dosage/administration | 6mg over 1-2 seconds W/ 20mL saline flush. If conversion doesn't occur within 1-2 minutes, 12mg followed by 20mL flush. 12 mg
dosage may be repeated
rapid IV bolus
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| Adenosine Ped dosage/administration | .1 mg/kg over 1-2 sec with saline flush. .2 mg/kg may be given as second dosage if needed rapid IV bolus
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| adenosine onset | 30 seconds
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| adenosine duration | 10 seconds
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| adenosine peak effect | ???
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| amiodarone class | antidysrhythmia
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| amiodarone MOA | prolongation of action potential, non competitive Alpha+Beta sympathetic blocking effects, blocks calcium channels
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| amiodarone indications | pts w/ absent VS and either VF or VT on monitor, suppression of VF refractory to defibrillation, suppression of VT refractory to defibrillation
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| amiodarone contraindications | hypothermia induced cardiac arrest, pt in renal failure, 2nd and 3rd degree heart block, medication induced ventricular dysrythmias, hypotension, bradycardia, Torsades de pointes, profound sinus bradycardia, known hypersensitivity
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| amiodarone adverse effects | hypotension, bradycardia, PEA, CHF, nausea, fever, thrombocytopenia, pulmonary fibrosis, accute respiratory distress syndrome
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| amiodarone how its supplied | 150 mg/3mL ampul, 150mg/3mL pre filled syringe
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| amiodarone adult dose/route | 300mg initial, 150mg if refractory or VF/VT returns Slow IV/IO push
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| amiodarone ped dose/route | pulseless arrest-5mg/kg VT-5mg/kg over 5 min (only with MC order) slow IV/IO push
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| amiodarone onset/peak effect/duration | 5-15 min/variable/variable
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| atropine sulfate class | anticholinergic agent
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| atropine MOA | inhibits aacetylcholine @ postganglionic parasympathetic neuroeffector sites, increases HR in bradycardic dysarrythmias, blocks acetylcholine excess in organophosphate poisoning
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| atropine indications | hemodynamically significant bradycardia, organophosphate poisoning, nerve gas exposure
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| atropine contraindications | tachycardia, hypersensitivity, narrow angle glaucoma, unstable cardiovascular status in accute hemorrhage
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| atropine adverse effects | headache, nausea, vomiting, dizziness, palpitations, tachycardia dysrythmias, blurred vision, dry mouth, urinary retention, paradoxical bradycardia, flushed/hot/dry skin
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| atropine how its supplied | 1mg/10mL prefilled syringe, 2.1 mg DuoDote auto injector
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| atropine adult dose/route | bradycardia .5 mg IV bolus every 3-5 minutes PRN to max of 3mg total
Organophosphate poisoning 2mg IV/IM every 5 minutes PRN
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| atropine Onset/peak effect/duration | immediate/1-2 minutes/2-6 hours
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| Aspirin class | Platelet inhibitor/NSAID
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| aspirin MOA | prostaglandin inhibition, prevents platelet formation
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| aspirin indications | chest pain suggstive of accute MI, pt w/ previous cardiac Hx presenting with chest pain consistent w/ cardiac ischemia
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| aspirin contraindications | hypersensitivity, GI bleed
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| aspirin adverse effects | heartburn, GI bleeding, nausea, vomiting, wheezing, prolonged bleeding
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| aspirin how its supplied | 81mg chewable tablets
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| aspirin adult dose and route | MI 324mg PO
pain relief (analgesic) 325-600 mg every 4-6 hrs PO
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| aspirin ped dose and route | MI ????
analgesic 10-15 mg/kg every 4-6 hrs PO
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| aspirin onset/peak effect/duration | 5-30 min/1-3 hr/4-6 hr
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| Cipro Class | Synthetic Antimicrobial Agent
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| Cipro MOA | Treatment of exposure to microorganisms and anthrax inhalation
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| Cipro Indications | Treatment of infections caused by microorganisms, and postexposure inhalation anthrax
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| Cipro Contrindications | hypersensitivity
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| Cipro Adverse Reactions | Nausea, vomiting, diarrhea, abdominal pain, headache, restlessness, rash
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| Cipro How it's supplied | 500mg tablets
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| Cipro Adult Dosage/ROute | 500mg q 12 hrs for 60 days for anthrax/PO
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| Cipro Ped Dosage/Route | 15mg/kg q 12 hrs for 60 days, 6-10mg/kg for infections/PO
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| Cipro duration | Up to 12 hrs
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| Doxycycline Class | tetracycline antibiotic
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| Doxycycline MOA | Antibiotic effects
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| Doxycycline Indications | Brucellosis, fever from biological agent, pneumonic plague, Typhoidial Tuleremia, Anthrax exposure, acne
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| Doxyxycline contraindications | Hypersensitivity
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| Doxycycline adverse effects | Anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis, rash
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| Doxycycline How its supplied | 75, 100, 150 mg tablets
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| Doxycycline adult dose/route | 200mg first day, 100mg a day after that /PO
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| doxycycline ped dose/route | 4.4mg/kg first day, 2.2 mg/kg after that PO
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| Doxycycline onset, peak effect, duration | 1-2 hr/1.5-4 hr/12 hr
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| Captopril Class | ACE Inhibitor
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| Captopril MOA | Supression of renin-angiotensin-aldosterone system, afterload reduction, arterial vasodilaton
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| Captopril Indication | HTN, HTN associated w/ acute pulmonary edema
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| Captopril Contraindications | Hypersensitivity
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| captopril adverse effects | rash, fever, taste impairment, angioedema, cough, hypotension
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| Captopril how its supplied | 25mg tablet
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| captopril adult dose/route | 25mg/SL
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| captopril ped dose/route | not recommended
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| captopril onset/peak effect/duration | within 5 min/variable/variable
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| Dextrose 50% class | Hypertonic solution
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| Dextrose MOA | rapidly increases serum glucose levels
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| Dextrose indications | signs and symptoms consistent w/ hypoglycemia, confirmed hypoglycemia
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| dextrose contraindications | intracranial hemorrhage, increased intracranial pressure
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| dextrose adverse effects | extravasation leads to tissue necrosis, warmth, pain, burning, thrombophlebitis, rhabdomyositis
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| dextrose how its supplied | 25Gm/50mL prefilled syringe
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| dextrose adult dose/route | 25GM PRN/IV
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| dextrose ped dosage/route | <2yrs 1-2mL/kg 25% >2yrs 1-2mL/kg 50%
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| dextrose onset/peak effect/duration | <1 min/variable/variable
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| Diazepam(Valium)class | Benzodiazapine
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| Diazepam MOA | Potentiates effects of inhibitory neurotransmitters, raises seizure thresholds, induces amnesia and sedation
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| Diazepam Indications |
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Created by:
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