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Test #3

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What do phenol/phenol derivatives do?   Denature proteins and disrupt membrane  
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Phenol   first antiseptic/disinfectant; used as an aqueous solution; good against mycobacterium  
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Cresols   disinfectant; highly concentrated milky looking emulsion; ex. original lysol  
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Hexachlorophene   antiseptic; very powerful; bacteriostatic film at ppm doses; found to have caused brain damage in preterm infants  
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Triclosan   antiseptic product with antibacterial activity found in some soaps and embedded in household items; found in sponges, cutting boards, toys, toothpaste  
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Phenol coefficient testing   used as a standard to compare other disinfectants with; this has been replaced by other testing methods  
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What do biguanides do?   disrupt membrane  
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Chlorhexidine   a biguanide; replaced hexachlorophene because more effective and less toxic; kills G+ and G- bacteria, some fungi and viruses but not spores; microbiostatic film on skin surfaces; found in surgical scrubs and mouthwash  
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Which alcohol works best?   isopropanol (rubbing alcohol); best as antiseptic/disinfectant  
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Tincture   a solution in which the solvent is alcohol  
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What does a surfactant do?   disrupt membrane and possibly denature protein; it decreases surface tension of liquids making them wetter and improving cleaning and penetrating ability of the product  
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Examples of quaternary ammonium compounds   Zephiran (not really used anymore because not very effective); Cepacol  
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examples of halogens   iodine and chlorine  
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What form of iodine is best to use on the skin?   iodophors (organic derivatives)- much safer on the skin than 1% tincture  
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Bleach   a chlorine; strongest and cheapest disinfectant  
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Compressed chlorine gas   water treatment; may produce chlorinated hydrocarbons (carcinogenic) when polluted water is chlorinated; alternative is use chloramine- doesn't form carcinogens and is slower working  
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Oxidizing agents   oxidize cell components and denature proteins; various chemicals that release free oxygen; ex. hydrogen peroxide and ozone  
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What is silver nitrate used for?   clear aqueous solution (turns black in light); was used in the eyes of infants to prevent gonorrheal infection  
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Aldehydes   inactivate proteins and nucleic acids; ex. formaldehyde and glutaraldehyde  
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Formaldehyde   used as formalin; embalming fluid, vaccine production, gaseous sterilant  
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Glutaraldehyde   used as 2% aqueous solution; capable of "cold sterilization" in 10 hours; requires activator and is only good for 2-3 weeks; requires sterile water rinse to get rid of left behind residue (toxic chemical)  
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Why must items treated with ethylene oxide be well aerated prior to use?   needs to be aerated because it sticks to whatever is being treated and leaves behind a toxic residue; this residue can be irritatinga and carcinogenic  
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Which are effective products for controlling Mycobacterium?   phenol, ethanol,bleach  
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What are useful products for eliminating endospores?   bleach works fair against endospores  
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