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Bacterial Diseases of the Urogenital Tract

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Question
Answer
What is the reservoir of the Neisseria gonorrhoeae?   humans are the only source  
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what are the gram reactivity and morphology of Neisseria?   bean-shaped pairs of cocci of Neisseria are gram-negative  
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How is gonorrhea diagnosed?   dx as infectious with oxidase-pos., gram-neg, diplococci from urethral exudate and species confirmed by sugar fermentation tests  
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How is gonorrhea treated and prevented?   tx--penicillin/cephtriaxone--risk decreases with use of condoms--no vaccine  
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How does N. gonorrhoeae overcome the flushing mechanism produced by urine flow?   use of pili holdfasts  
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Describe the shape, motility, and transmission of treponema pallidum   coiled, spiral-shaped, highly motile, and sexually transmitted  
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Primary stage of syphilis   pt exhibits chancre full of organisms  
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Secondary stage of syphilis   rash on palms and feet with fluid full of organisms  
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Tertiary stage of syphilis   years after initial inf, pt suffers from gumma--distruction of soft tissue of bone, heart, brain internal viscera, etc--absence of bacteria  
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How is syphilis treated?   with penicillin in first two stages, antibacterials useless during tertiary stage  
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what is general paresis?   approx 20 yrs after syphilis inf. general group of mental illnesses--dementia--emotional instability, memory loss, impaired judgment, delusions, hallucinations, loss of vision, eye damage, speech defects  
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How often is chlamydial infection asymptomatic?   70% of females and 30% of males  
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Where must drugs travel to be effective against Chlamydia?   drugs must penetrate into host cell, then into inclusion body, finally into bacteria to be effective against Chlamydia  
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