SLE
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each of the black spaces below before clicking
on it to display the answer.
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| What are the different forms of lupus? | SLE, Discoid lupus erythematosus, and drug induced lupus
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| What genetically triggers lupus? | TREX1 gene mutation
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| Who is most effected by Lupus? | non-white women during childbearing years
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| What is the most common infection in lupus pts? | pneumonia
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| How is the disease spectrum of lupus? | mild-rashes,arthritis, fatigue moderate-pericarditis, low blood count, severe-renal failure, seizures
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| What are the disease specific tests for lupus? | positive anti-Smith, positive anti-double strand, positive anti-phospolipid antibody, false-positive syphilis, RPR, ENA IgG Beadchip test (can detect 6 autoantibodies), Anit RO, Anti LA
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| Why is it important to know if the pt is anti-phospolipid antibody positive? | cause these pts are more likely to form clots and need to be on anticoagulant therapy
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| What is the mnemonic associated w lupus? | SOAP BRAIN MD Serositis, Oral ulcers, Arthritis, Photo-sensitivity, Blood disorder, Renal disorder, Antinuclar antibodies, Immunological disorder, Neurological disorder, Malar rash, Discoid rash
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| What is the med used for advanced kidney damage in lupus patients? | cellcept
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| What is prasterone? | it is a male hormone used to counteract the amount of estrogen
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| What type of meds are paquenil and aralen? | anti-malarial drugs, used after cortecosteriods are no longer working
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| What does Belimumab do? | decrease b cell production
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| How does Rituximab work? | kills B cells
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| How does infliximab work? | binds inflammation signals
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| What other diseases does lupus put you at risk for? | leukemia, lymphoma, breast CA, heart dz
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