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drugs for cancer

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analgesic ladder (3 steps)   step 1: mild to moderate pain use non-opiod analgesic and NSAIDs and acetaminophen. step 2: more severe pain-add opiod analgesic, oxycodone, hydrocodone. step 3: substitute powerful opiod--morphine, fentanyl  
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non-opiod analgesic are   NSAIDs( aspirin, ibuprofen ) and acetaminophen (tylenol)  
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drug selection for cancer patients   use preferred choice of pure opiod agonists, opiod rotation, dosage should be individualized. use the following with caution methadone (dolophine), levorphanol (levo-dromoran), codeine. AVOID meperidine ( DEMEROL )  
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side effects of pure opiod   respiratory depression, constipation, sedation, nausea and vomitting.  
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what are adjuvent analgesics?   used to compliment the effects of opiods-not as a substitute. can be tricyclic antidepressants (amitriptyline aka elavil). antiseizure meds, local anesthetics/antidysrhymics. CNS stimulants, antihistamines ( hydroxyzine aka istaril ). glucocorticoids  
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invasive procedures   neurolytic nerve block, neurosurgery,trumor surgery, radiation therapy  
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physical interventions include:   heat, cold, massage, exercise, acupuncture  
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psychosocial interventions include:   relaxation and imagery, cognitive distraction, peer support groups  
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older adults related to pain   have heightened drug sensitivity, undertreatment of pain, increased risks of side effects and adverse interactions  
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misconceptions for older adult   beliee that elderly patients are insensitive to pain, belief that elder can tolerate pain well, belief that elderly pateints are highly sensitive to opiod side effects  
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