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Epi,Atropine, Amiodarone

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Term
Definition
Amiodarone Classification   Antiarrythmic  
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Amiodarone Action/Kinetics   Blocks Sodium channels at rapid pacing frequencies. Decreases sinus rate. Increases PR and QT intervals. After IV, it relaxes vascular smooth muscle and reduces afterload.  
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Amiodarone Indications   VF and pulseless VT refractory to Defibrillation. Stable VT and Unstable VT refractory to cardioversion  
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Amiodarone Dosage Adult   Pulseless VF/VT: 300mg IV push (Consider repeating: 150mg IV push in 3-5 min) Wide Complex Tachycardia(Stable)- 150mg rapid infusion IV/IO  
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Amiodarone Dosage Pedi   Pulseless VT/VF: 5mg/kg IV/IO Bolus  
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Atropine Classification   Antiarrythmic, anticholigneric, antidote  
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Atropine Action/Kinetics   Anticholinergic that inhibits the acetylcholine at the parasympathetic neuroeffector junction, blocking vagal effects on the SA and AV nodes. This enhances conduction through the AV node and speeds heart rate.  
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Atropine Indications   Hemodynamically significant bradycardia. Asystole, organophosphate poisoning or nerve agent exposure. PEA with slow complex rate  
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Atropine Dosage Adult   Bradycardia- 0.5mg-1.0mg IV/IO every 3-5min as needed up to 3mg. Asystole- 1mg IV/IO ever 3-5min up to 3mg Organophosphate poisoning- 2mg until patient is stable  
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Atropine Dosage Pedi   Bradycardia/Asystole- .02mg/kg IV/IO up to 0.5(child) and 1.0(adolescent) may repeat once in 5min.  
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Epi Classifications   Sympathmimetric, cardio stimulant, broncodilator, antiallergic, vasopressor  
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Epi Action/Kinetics   Stimulates alpha and beta-adrenergic receptors within sympathetic nervous system. strengthens myocardial contraction and increases cardiac rate. Increases myocardial and cerebral blood flow during CPR  
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Epi Indications   Cardiac Arrest, VF, Pulseless VT, Asystole, PEA, Anaphalixis, Asthma(COPD)  
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Epi Dosage Adult   Cardiac Arrest- 1mg (1:10000) IV/IO every 3-5 min during CPR. No max Anaphylaxis- 0.3-0.5 (1:1000) IM/SQ: Good perfusion 0.3-0.5 (1:10000) IV/IO: Poor perfusion or hypotension Asthma- 0.3-0.5mg IM/SQ (1:1000)  
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Epi Dosage Pedi   Cardiac Arrest- 0.01mg/kg (1:10000) IV/IO up to 1mg Anaphylaxis- 0.01mg/kg (1:1000) IM/SQ up to 0.3mg  
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