Epi,Atropine, Amiodarone
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Amiodarone Classification | Antiarrythmic
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Amiodarone Action/Kinetics | Blocks Sodium channels at rapid pacing frequencies. Decreases sinus rate. Increases PR and QT intervals. After IV, it relaxes vascular smooth muscle and reduces afterload.
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Amiodarone Indications | VF and pulseless VT refractory to Defibrillation. Stable VT and Unstable VT refractory to cardioversion
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Amiodarone Dosage Adult | Pulseless VF/VT: 300mg IV push (Consider repeating: 150mg IV push in 3-5 min)
Wide Complex Tachycardia(Stable)- 150mg rapid infusion IV/IO
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Amiodarone Dosage Pedi | Pulseless VT/VF: 5mg/kg IV/IO Bolus
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Atropine Classification | Antiarrythmic, anticholigneric, antidote
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Atropine Action/Kinetics | Anticholinergic that inhibits the acetylcholine at the parasympathetic neuroeffector junction, blocking vagal effects on the SA and AV nodes. This enhances conduction through the AV node and speeds heart rate.
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Atropine Indications | Hemodynamically significant bradycardia. Asystole, organophosphate poisoning or nerve agent exposure. PEA with slow complex rate
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Atropine Dosage Adult | Bradycardia- 0.5mg-1.0mg IV/IO every 3-5min as needed up to 3mg.
Asystole- 1mg IV/IO ever 3-5min up to 3mg
Organophosphate poisoning- 2mg until patient is stable
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Atropine Dosage Pedi | Bradycardia/Asystole- .02mg/kg IV/IO up to 0.5(child) and 1.0(adolescent) may repeat once in 5min.
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Epi Classifications | Sympathmimetric, cardio stimulant, broncodilator, antiallergic, vasopressor
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Epi Action/Kinetics | Stimulates alpha and beta-adrenergic receptors within sympathetic nervous system. strengthens myocardial contraction and increases cardiac rate. Increases myocardial and cerebral blood flow during CPR
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Epi Indications | Cardiac Arrest, VF, Pulseless VT, Asystole, PEA, Anaphalixis, Asthma(COPD)
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Epi Dosage Adult | Cardiac Arrest- 1mg (1:10000) IV/IO every 3-5 min during CPR. No max
Anaphylaxis- 0.3-0.5 (1:1000) IM/SQ: Good perfusion
0.3-0.5 (1:10000) IV/IO: Poor perfusion or hypotension
Asthma- 0.3-0.5mg IM/SQ (1:1000)
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Epi Dosage Pedi | Cardiac Arrest- 0.01mg/kg (1:10000) IV/IO up to 1mg
Anaphylaxis- 0.01mg/kg (1:1000) IM/SQ up to 0.3mg
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