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Epi,Atrpne,Amiodaron

Epi,Atropine, Amiodarone

TermDefinition
Amiodarone Classification Antiarrythmic
Amiodarone Action/Kinetics Blocks Sodium channels at rapid pacing frequencies. Decreases sinus rate. Increases PR and QT intervals. After IV, it relaxes vascular smooth muscle and reduces afterload.
Amiodarone Indications VF and pulseless VT refractory to Defibrillation. Stable VT and Unstable VT refractory to cardioversion
Amiodarone Dosage Adult Pulseless VF/VT: 300mg IV push (Consider repeating: 150mg IV push in 3-5 min) Wide Complex Tachycardia(Stable)- 150mg rapid infusion IV/IO
Amiodarone Dosage Pedi Pulseless VT/VF: 5mg/kg IV/IO Bolus
Atropine Classification Antiarrythmic, anticholigneric, antidote
Atropine Action/Kinetics Anticholinergic that inhibits the acetylcholine at the parasympathetic neuroeffector junction, blocking vagal effects on the SA and AV nodes. This enhances conduction through the AV node and speeds heart rate.
Atropine Indications Hemodynamically significant bradycardia. Asystole, organophosphate poisoning or nerve agent exposure. PEA with slow complex rate
Atropine Dosage Adult Bradycardia- 0.5mg-1.0mg IV/IO every 3-5min as needed up to 3mg. Asystole- 1mg IV/IO ever 3-5min up to 3mg Organophosphate poisoning- 2mg until patient is stable
Atropine Dosage Pedi Bradycardia/Asystole- .02mg/kg IV/IO up to 0.5(child) and 1.0(adolescent) may repeat once in 5min.
Epi Classifications Sympathmimetric, cardio stimulant, broncodilator, antiallergic, vasopressor
Epi Action/Kinetics Stimulates alpha and beta-adrenergic receptors within sympathetic nervous system. strengthens myocardial contraction and increases cardiac rate. Increases myocardial and cerebral blood flow during CPR
Epi Indications Cardiac Arrest, VF, Pulseless VT, Asystole, PEA, Anaphalixis, Asthma(COPD)
Epi Dosage Adult Cardiac Arrest- 1mg (1:10000) IV/IO every 3-5 min during CPR. No max Anaphylaxis- 0.3-0.5 (1:1000) IM/SQ: Good perfusion 0.3-0.5 (1:10000) IV/IO: Poor perfusion or hypotension Asthma- 0.3-0.5mg IM/SQ (1:1000)
Epi Dosage Pedi Cardiac Arrest- 0.01mg/kg (1:10000) IV/IO up to 1mg Anaphylaxis- 0.01mg/kg (1:1000) IM/SQ up to 0.3mg
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