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Chapter 8, 9 & 10

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Term
Definition
Excess Energy   -is stored fat used for energy between meals  
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Energy Balance   -energy in = energy out -shift in balance causes weight change -1 lb = 3,500 cal  
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Hunger   -Physiological response to nerve signals and chemical messengers -Influences: include hormones, nutrients in blood, preceding meal, external temperature, exercise and others  
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Satiation   stop hunger  
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Satiety   not to start eating again  
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Sustaining Satiety & satiation   -nutrient composition  
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Nutrient composition   -protein is the most satiating -High fiber foods satiating -Both give strong satiety signals -high fats foods: strong satiety but slower to work  
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Hypothalamus   -control center for eating -integrates messages: energy intake, expenditure, storage -Biological molecules regulate food intake  
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Biological molecules   -Ghrelin, adiponeptin, leptin  
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Energy Out   Thermogenisis  
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Thermogenis   -Basal metabolisms, physical activity, food consumption, adaptation  
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Basal Metabolism   -about 2/3 energy expended & basic processes of life -Basic metabolic rate: indiv. variation, weight & lean tissue will increase  
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Physical activity   -voluntary movement of skeletal muscle -amount of energy needed will increase with greater: muscle mass, body weight & activity -FITT influence  
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Thermic Effect of Food   -Increase GI tract functioning in response to food presence: releases heat -10% of energy in take -high protein foods higher losses than high fat foods  
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High waist circumference   -indicator of fat distribution & central obesity -Women: greater than 35 inch. -Men: greater than 40 inch.  
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Other techniques for body composition   - more precise measurements -skinfolds, hydrostatic weighing, bioelectrical impedance, dexa, bodpod  
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Health risks associated with body fat & body weight   -body weight & fat distribution correlated with disease risk & life expectancy -diabetes, hypertension, CVD & sleep apnea  
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Risks cause by being underweight   -fighting against wasting disease -menstrual irregularity & infertility -Osteoporosis & bone functioning  
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Fat cell development   -stored in fat cells of adipose tissue -Fat cells increase in number during childhood & puberty -energy out exceeds energy in: decrease size & no change in #  
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Gene code for Leptin protein's affect on obesity   -made in adipose tissue as hormone in hypothalamus -promotes negative energy balance -suppresses appetite & increase energy expenditure  
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Uncoupling proteins   -proteins involved in metabolism -higher in brown adipose tissue -results in greater loses of energy as heat  
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Agressive treatments for obesity: Orlistat   -inhibits pancreatic lipase in GI tract -blocks dietary fat digestion & absorption -side effects: gas, frequent bowel movements  
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Agressive treatments for obesity: Phentermine and diethylpropion   -enhances release of neurotransmitter -norepinepherine release to brain & reduces food intake -Side effects: High blood pressure & insomnia  
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Agressive treatments for obesity: Surgery   -clinically serves obesity -reduce food capacity in stomach: gastric bypass or banding -effectively limits food intake -Liposuction: reduce deposits by removing fat cells  
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Eating plans   -remember water -focus on fiber: low in energy but high in nutrients -choose fats sensibly: lower fat lowers density -select carb carefully -watch for empty cals  
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Vitamin Overview   -support nutritional health -Differ from macronutrients: Structure & function (no energy yield) -composed of carbon, hydrogen, oxygen & nitrogen -toxicity: more not always better, levels higher than UL cause problems -  
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Overall Vitamin B's   -coenzymes assist with release of energy -with coenzymes, most enzymes cant function  
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Thiamin   -deficiency: Malnourishment & alcoholics -Beriberi disease: dry (nervous system) & wet (cardiovascular system) -Toxicity: no adverse effects or UL  
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Riboflavin   -major food sources: milk & milk products -Destruction: ultraviolet light, irradiation -not destroyed by cooking  
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Niacin   -Body manufactures from tryptophan: only occurs after protein synthesis needs have been met -deficiency: Pellagra (diarrhea, dermatitis, dementia)  
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Niacin toxicity   -naturally occurring: no harm -supplements: niacin "flush" -large doses of nicotinic acid: reduces LDL's -less vulnerable to food preparations losses  
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Biotin   -adequate intake is to difficult to determine -Deficiencies: rare because found in many foods, can be induced by eating large amount of egg whites & results in skin rash + hair loss -toxicity: no UL  
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Pantothenic Acid   -part of chemical structure of Coenzyme A -role in body: energy metabolism, synthesis of fat & neurotransmitters -recommendation: AI -Deficiency: rare because widespread in many foods -toxicity: no UL, none reported  
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B6   -recommendation RDA -Deficiency: symptoms= neurological, depression, confusion, anemia -alcohol & isoniazid can reduce deficiency -toxicity: irreversible nerve damage, -best food sourced= meat, poultry, fish  
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Folate Deficiency   -neural tube defects like spina bifida -Supplements: 1 month b4 conception & through 1st trimester -fortified grain products helpful -risk: may mask vitamin B12 deficiency  
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Folate in general   -May prevent heart disease: breakdown of homocysteine, prevents blood clots -decrease risks of heart attack, stroke or death from CVD -Cancer: may prevent colon cancer, timing of supplements could increase risk if already cancer is initiated  
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Vitamin B12   -recommendations: RDA established -Deficiency: “Pernicious Anemia”, vegans may precipitate after long time -symptoms of vitamin B12 deficiency  
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