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Pharmacology

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Term
Definition
AKA Nitrostat, is a smooth muscle relaxant that reduces peripheral vascular resistance, BP, venous return, and cardiac workload.   Nitroglycerin  
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Indicated for chest pain associated w angina and AMI, acute pulmonary edema.   Nitroglycerin  
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Contraindicated for tolerance to nitrates, severe anemia, head trauma, hypotension, increased ICP, pts taking sildenafil, glaucoma, shock.   Nitroglycerin  
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May induce headache, sometimes severe, is light sensitive and will lose potency when exposed to the air.   Nitroglycerin  
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Dosed at 1 tab (.4mg) up to 3 tabs, or 1 spray (.4mg) up to 3 sprays in 15min or half- 1 inch topical ointment.   Nitroglycerin  
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A self administered analgesic gas composed of 50% oxygen and 50% Nitrous oxide.   Nitrous Oxide  
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AKA Nitronox its effects only last 2-5min after administration ceases.   Nitrous Oxide  
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Indicated for musculoskeletal, burn, and ischemic chest pain, severe anxiety (including hyperventilation)   Nitrous Oxide  
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Contraindicated for possible bowel obstruction, pneumothorax or tension pneumothorax, COPD, head injury, impaired mental status, drug intoxication.   Nitrous Oxide  
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Self administered inhalation until pain is relieved or the pt drops the mask.   Nitrous Oxide  
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A naturally occuring catecholemine and causes vasoconstriction, cardiac stimulation, and increased BP, myocardial O2 demand, and coronary blood flow.   Norepinephrine  
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Indications Refractory hypotension and neurogenic shock.   Norepinephrine  
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Contraindicates of hypotension due to hypovolemia.   Norepinephrine  
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AKA Levophed dosed at 0.1-0.5mcg/kg/min IV/IO, titrated to response.   Norepinephrine  
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AKA Zofran is a selective seretonin receptor antagonist preventing nausea and vomiting.   Ondansetron  
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Indicated for nausea and vomiting.   Ondansetron  
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Cautioned for pregnancy, nursing mothers, and kids under 3.   Ondansetron  
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Dosage of 4-8mg IV over 1-5min   Ondansetron  
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An oderless, colorless, tasteless gas, essential for life, one of the most important emergency drugs.   Oxygen  
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Indicated for anticipated hypoxia, or in any medical or trauma pt to improve respiratory eficiency.   Oxygen  
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Cautioned for COPD, and very prolonged administration of high concentrations in the newborn.   Oxygen  
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Dosage is 100% by inhalation or IPPV.   Oxygen  
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A naturally occuring hormone, AKA Pitocin, that causes the uterus to contract, therby inducing labor, encouraging delivery of the placenta, and controlling post partum hemorrhage.   Oxytocin  
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Indicated for severe postpartum hemorrhage.   Oxytocin  
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Contraindicated in prehospital administration before delivery on infant/s   Oxytocin  
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Dosage of 3-10units IM afer delivery of the placenta. 10-20units in 500ml of D5W or NS IV titrated to effect.   Oxytocin  
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A nondepolarizing neuromuscular blocked that causes paraylis wo bronchospasm or hypotension.   Pancuronium  
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It does not cause the facilitations associated w polarizing agents.   Pancuronium  
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Indicatd to facilitate endotracheal intubation.   Pancuronium  
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Contraindicated for bromides or tachycardia.   Pancuronium  
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Dosage of .04-0.1mg/kg IV   Pancuronium  
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A long acting barbiturate anticonvulsant w sedative and hypnotic effects that limits the spread of seizure activity.   Phenobarbital  
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Indicated for seizures, status epilepticus, acute anxiety.   Phenobarbital  
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Contraindicated for hypersensitivity to barbiturates.   Phenobarbital  
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Dosage of 100-300mg slow IV/IM   Phenobarbital  
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Is a derivative related to phenobarbital that reduces the spread of electrical discharges in the motor cortex and inhibits seizures.   Phenytoin  
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It also has antidysrhythmic properties that "could depress spontaneous ventricular depolarization."   Phenytoin  
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Indicated for seizures, status epilepticus, cardiac dysrhythmias secondary to digitalis toxicity.   Phenytoin  
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Contraindicated for seizures due to hypoglycemia, sinus brady, heart block, Adams-Stokes syndrome   Phenytoin  
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AKA Dilantin is dosed at 15-18mg/kg slow IV for seizures/status epilepticus.   Phenytoin  
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Give 100mg slow IV (over 5 min) to a max 1000mg for dysrhythmias.   Phenytoin  
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Reactivates cholinesterase and reinstitutes the degrading of acetylcholine and restores normal neuromuscular transmission.   Pralidoxime  
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Used to reverse severe organophosphate poisoning.   Pralidoxime  
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Indicated for Organophosphate poisoning   Pralidoxime  
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Contraindicated for carbamate insecticides (Sevin) inorganic phosphates, and organophosphates wo anticholinesterase activity.   Pralidoxime  
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Contraindicated for asthma, peptic ulcer disease, severe cardiac disease, or pts receiving aminophylline, theophylline, morphine, succinylcholine, resperidine, or phenothiazines.   Pralidoxime  
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AKA 2-PAM is dosed at 1-2g in 250-500ml NS infused over 30 min, or 1-2g I /CQ if IV not feasible.   Pralidoxime  
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Is an antidysrhythmic that prolongs ventricular repolarization, slows conduction, and decreases myocardial excitability.   Procainamide  
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Indicated for V-Fib and Pulseless V-Tach refractory to lidocaine   Procainamide  
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AKA Pronestyl, it is dosed at 20mg/min IV drip up to 17mg/kg to effect, then 1-4mg/min   Procainamide  
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An anticholinergic agent that enhances the effects of analgesics and is a potent antiemetic.   Promethazine  
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Indicated for nausea and vomiting, motion sickness, to enhance the effects of analgesics, to induce sedation.   Promethazine  
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Contraindicated for hypersensitivity to phenothiazines.   Promethazine  
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AKA Phenergan, it is dosed at 12.5-25mg IV/IM/PR   Promethazine  
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