psychopharm
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| Antabuse | Generic: Disulfiram
Category: Alcohol abuse therapy adjuncts/Aversion therapy
MOA: Inhibits aldehyde dehydrogenase (enzyme from ethanol)
Major Side Effects: Hepatotoxicity and death if taken with alcohol
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| Abilify | Ariprozole
Category: Atypical Anti-Psychotic
MOA: Agonist at dopamine D2 & serotonin 5-HT1A receptors; antagonist at 5-HT2A.
Major Side Effects: SI, agranulocytosis, neuroleptic malignant syndrome, fatigue, anxiety & EPS. Avoid in elderly w/dementia
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| Seroquel | Quietapine
Category: 2nd Gen. Anti-Psychotic
MOA: Antagonist at multiple neurotransmitter receptors (dopamine & serotonin)
Major Side Effects: SI, DKA, agranulocytosis, neuroleptic malignant syndrome, tardive dyskinesia. Avoid in elderly w/dementia
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| Risperdal | Risperidone
Category: Atypical Anti-Psychotic
MOA: antagonist for dopamine D2 & serotonin 5-HT2 receptors
Major Side Effects: SI, DKA, agranulocytosis, neuroleptic malignant syndrome, CVA & tardive dyskinesia. Avoid in elderly w/dementia.
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| Carbolith | Lithium
Category: Mood stabilizer
MOA Alters cation transport in nerve and muscle. May also influence reuptake of neurotransmitters
Therapeutic effect: Prevents/decreases incidence of acute manic episodes. Tolerance greater during acute manic phas
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| Depakote | Valproic acid
Category: anticonvulsants
MOA: Increases level of GABA. Suppression of seizures. Decreased manic episodes and migraine headaches. Side Effects: SI, pancreatitis, hepatotoxicity, behavioral deterioration,
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| Topomax | Topiramate
Category: mood stabilizer, anticonvulsant
MOA: Blocks Na+ in neurons; decreases seizures. Not used often
Major side effects: SI, increases seizures, ataxia, dizziness, diplopia, nystagmus, sedation, impaired memory, paresthesia
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| Lamictal | Lamotrigine
Category: anticonvulsants
MOA: Inhibits Na+ transport. Decreases incidence of seizures
Side effects: Aseptic meningitis, SI, hepatic failure, Stevens-Johnson syndrome, Multi-organ hypersensitivity reactions, ataxia, dizziness
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| Buspar | Buspirone
Category: Antianxiety
MOA: Binds to serotonin and dopamine receptors in the brain; Increases norepinephrine metabolism in the brain.
Side Effects: Dizziness, drowsiness, headache, insomnia, weakness, blurred vision, palpitation, tachycardia
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| Tenex | Guanfacine
Category: Antihypertensive
MOA: Stimulates CNS alpha2 adrenergic receptors, producing a decrease in sympathetic outflow of heart, kidneys, & blood vessels.
Side Effects: Headache, drowsiness, erectile dysfunction, weakness.
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| Wellbutrin | Bupropion
Category: Antidepressant
MOA: Decreases neuronal reuptake of dopamine in the CNS.
Side Effects: Seizures, suicidal thoughts/behaviors, agitation, headache, tremor, nausea, vomiting.
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| Cogentin | Benzotropine
Category: Antiparkinson agent & drug induced extrapyramidal reactions.
MOA: Blocks cholinergic activity in the CNS; restores natural balance of neurotransmitters in CNS.
Side Effects: Blurred vision, HA, sedation, hallucinations, arrhythmi
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| Dolophine | Generic: Methadone
Category: Opioid analgesic
MOA: Narcotic agonist-analgesic of opiate receptors; inhibits ascending pain pathways
Side effects: N&V, Seizures, sedation, respiratory depression, bradycardia and hypotension
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| Ativan | Generic: Lorazepam
Route/ Dose: 0.5-2mg/day (divided doses initially)
Category:Anxiloytic. Pre-operative sedation
MOA:Depressed CNS potentiating GABA
Nursing Responsibilities: Withdrawal slowly
Major side effects: dizziness, drowsiness,depe
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| Klonopin | Generic: Clonazepam
Route/ Dose: 0.5-3mg x day (may increase dose by 0.5-1 mg q 3 days. no to exceed 20 mg x day
Category: Anxiolytic. Anti-seizure
MOA: produces sedative effects in CNS
Major side effects: drowsiness, behavioral changes
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| Librium | Generic: Chlordizepoxide
Route/ Dose: for anxiety 5-25mg 3-4 x day, for alcohol withdrawal 50-100mg
Category:anxiolytic. alcohol withdrawal
MOA:Depresses CNS by potentiating GABA
Major side effects: Dizziness, drowsiness, dependence
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| Xanax | Generic: Alprazolam
Route/ Dose: 0.25-0.50mg 2-3 x day. not to exceed 4mg/day
Category:Anxiolytic
MOA:CNS depression by acting on GABA
Nursing Responsibilities: avoid in elderly. taper slowly
Major side effects: drowsiness, dizziness, dependence
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| Prozac | Generic: Fluoxetine
Category: SSRI
Indications: Major depressive disorder, panic disorder, OCD, PMDD
Side Effects: Seizures, suicidal thoughts, serotonin syndrome, neuroleptic malignant syndrome
Nurses: Monitor for mood changes, suicidal tendencies.
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| Effexor | Generic: Venlafaxine
Category: SNRI
Indications: Major depressive disorder, GAD &SAD (XR), panic disorder
Side Effects:Seizures, suicidal thoughts, serotonin syndrome, neuroleptic malignant syndrome
Nursing:Monitor for mood changes, suicidal tendencie
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| Paxil | Generic: Paroxetine
Category: SSRI
Indications: Major depressive disorder, GAD, SAD, panic disorder, PTSD, PMDD
Side Effects:Seizures, suicidal thoughts, serotonin & neuroleptic malignant syndrome
Nursing:Monitor for mood changes, suicidal tendencies
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| Zoloft | Generic: Sertraline
Category: SSRI
Indications:Major depressive disorder,SAD, panic disorder, PTSD, PMDD
Side Effects:Seizures, suicidal thoughts, serotonin & neuroleptic malignant syndrome
Nursing:Monitor for mood changes, suicidal tendencies
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| Cymbalta | Generic: Duloxetine
Category: SNRI
Indications:Major depressive disorder, GAD, fibromyalgia, peripheral neuropathic pain
Side Effects:Seizures, suicidal thoughts, serotonin, SJ and neuroleptic mal. syn, erthyema multiforme
Nursing: Rash,suicidal thoug
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| Celexa | Generic: Citalopram
Category: SSRI
Indications:Depression. Unlabeled for PMDD, GAD, SAD, OCD, panic disorder, PTSD
Side Effects:Suicidal thoughts, serotonin & neuro. malig. syndrome, Torsade de Pointes
Nursing:Assess for mood changes,suicidal tenden
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| Proloxin | Generic: Fluphenazine
Category: Antipsychotic
Route and dose: For HCI form PO: 0.5-10 mg/day (max: 40mg daily) IM: 1.25-2.5 mg 6-8 hrs
SE: Extrapyramidal reactions, NMS, sedation, blurred vision, confusion, photosensitivity.
MOA: Alters effects of dop
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| Haldol | Generic: Haloperidol
Route and dose: PO .5-2.0 mg daily IM 2-5 mg q 1-8 hrs IV .5-5 mg q 30 minutes
Category: Antipsychotic; Tourette's Syndrome
SE: Extrapyramidal reactions, blurred vision, confusion, drowsiness, wt gain, neuroleptic malignant syndr
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| Thorazine | Generic: Chlorpromazine Route and dose: Psychosis 10-25 mg 2-4 daily Atimedtic: 10-25 mg q 4 hrs Category: Antipsychotic, Antimetic SE: NMS, sedation, blurred vision, confusion, photosensitivity MOA: Alters affects of dopamine in CNS. Alpha adrenergic
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| Zyprexa | Generic: Olanzapine, Rt & dose: PO 5-10 mg/day, target dose 10 mg/day, not to exceed 20 mg/day, IM 5-10 mg
Category: Antipsychotic, mood stabilizer
MOA: Antagonized dopamine and serotonin type 2 in the CNS.
SE: neuroleptic malignant syndrome, seiz
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| Clozaril | Generic: Clozapine, Rt & dose: PO 25 mg/day, target:300-450 mg/day, no more than 900 mg/day
MOA: Binds to dopamine receptors in the CNS.
SE: neuroleptic malignant syndrome, cardiac arrest, myocarditis, torsades, vent arrhythmias, agranulocytosis, leukop
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| Geodon | Generic: Ziprasidone, Rt & dose: PO 20 mg bid, IM 10 mg q 2 hr, up to 40 mg/day
MOA: Prob mediated by antagonism of dopamine type 2 & serotonin type 2
SE: neuroleptic malignant syndrome, prolonged QT, agranulocytosis
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