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brand namegeneric and MOA
Antabuse Generic: Disulfiram Category: Alcohol abuse therapy adjuncts/Aversion therapy MOA: Inhibits aldehyde dehydrogenase (enzyme from ethanol) Major Side Effects: Hepatotoxicity and death if taken with alcohol
Abilify Ariprozole Category: Atypical Anti-Psychotic MOA: Agonist at dopamine D2 & serotonin 5-HT1A receptors; antagonist at 5-HT2A. Major Side Effects: SI, agranulocytosis, neuroleptic malignant syndrome, fatigue, anxiety & EPS. Avoid in elderly w/dementia
Seroquel Quietapine Category: 2nd Gen. Anti-Psychotic MOA: Antagonist at multiple neurotransmitter receptors (dopamine & serotonin) Major Side Effects: SI, DKA, agranulocytosis, neuroleptic malignant syndrome, tardive dyskinesia. Avoid in elderly w/dementia
Risperdal Risperidone Category: Atypical Anti-Psychotic MOA: antagonist for dopamine D2 & serotonin 5-HT2 receptors Major Side Effects: SI, DKA, agranulocytosis, neuroleptic malignant syndrome, CVA & tardive dyskinesia. Avoid in elderly w/dementia.
Carbolith Lithium Category: Mood stabilizer MOA Alters cation transport in nerve and muscle. May also influence reuptake of neurotransmitters Therapeutic effect: Prevents/decreases incidence of acute manic episodes. Tolerance greater during acute manic phas
Depakote Valproic acid Category: anticonvulsants MOA: Increases level of GABA. Suppression of seizures. Decreased manic episodes and migraine headaches. Side Effects: SI, pancreatitis, hepatotoxicity, behavioral deterioration,
Topomax Topiramate Category: mood stabilizer, anticonvulsant MOA: Blocks Na+ in neurons; decreases seizures. Not used often Major side effects: SI, increases seizures, ataxia, dizziness, diplopia, nystagmus, sedation, impaired memory, paresthesia
Lamictal Lamotrigine Category: anticonvulsants MOA: Inhibits Na+ transport. Decreases incidence of seizures Side effects: Aseptic meningitis, SI, hepatic failure, Stevens-Johnson syndrome, Multi-organ hypersensitivity reactions, ataxia, dizziness
Buspar Buspirone Category: Antianxiety MOA: Binds to serotonin and dopamine receptors in the brain; Increases norepinephrine metabolism in the brain. Side Effects: Dizziness, drowsiness, headache, insomnia, weakness, blurred vision, palpitation, tachycardia
Tenex Guanfacine Category: Antihypertensive MOA: Stimulates CNS alpha2 adrenergic receptors, producing a decrease in sympathetic outflow of heart, kidneys, & blood vessels. Side Effects: Headache, drowsiness, erectile dysfunction, weakness.
Wellbutrin Bupropion Category: Antidepressant MOA: Decreases neuronal reuptake of dopamine in the CNS. Side Effects: Seizures, suicidal thoughts/behaviors, agitation, headache, tremor, nausea, vomiting.
Cogentin Benzotropine Category: Antiparkinson agent & drug induced extrapyramidal reactions. MOA: Blocks cholinergic activity in the CNS; restores natural balance of neurotransmitters in CNS. Side Effects: Blurred vision, HA, sedation, hallucinations, arrhythmi
Dolophine Generic: Methadone Category: Opioid analgesic MOA: Narcotic agonist-analgesic of opiate receptors; inhibits ascending pain pathways Side effects: N&V, Seizures, sedation, respiratory depression, bradycardia and hypotension
Ativan Generic: Lorazepam Route/ Dose: 0.5-2mg/day (divided doses initially) Category:Anxiloytic. Pre-operative sedation MOA:Depressed CNS potentiating GABA Nursing Responsibilities: Withdrawal slowly Major side effects: dizziness, drowsiness,depe
Klonopin Generic: Clonazepam Route/ Dose: 0.5-3mg x day (may increase dose by 0.5-1 mg q 3 days. no to exceed 20 mg x day Category: Anxiolytic. Anti-seizure MOA: produces sedative effects in CNS Major side effects: drowsiness, behavioral changes
Librium Generic: Chlordizepoxide Route/ Dose: for anxiety 5-25mg 3-4 x day, for alcohol withdrawal 50-100mg Category:anxiolytic. alcohol withdrawal MOA:Depresses CNS by potentiating GABA Major side effects: Dizziness, drowsiness, dependence
Xanax Generic: Alprazolam Route/ Dose: 0.25-0.50mg 2-3 x day. not to exceed 4mg/day Category:Anxiolytic MOA:CNS depression by acting on GABA Nursing Responsibilities: avoid in elderly. taper slowly Major side effects: drowsiness, dizziness, dependence
Prozac Generic: Fluoxetine Category: SSRI Indications: Major depressive disorder, panic disorder, OCD, PMDD Side Effects: Seizures, suicidal thoughts, serotonin syndrome, neuroleptic malignant syndrome Nurses: Monitor for mood changes, suicidal tendencies.
Effexor Generic: Venlafaxine Category: SNRI Indications: Major depressive disorder, GAD &SAD (XR), panic disorder Side Effects:Seizures, suicidal thoughts, serotonin syndrome, neuroleptic malignant syndrome Nursing:Monitor for mood changes, suicidal tendencie
Paxil Generic: Paroxetine Category: SSRI Indications: Major depressive disorder, GAD, SAD, panic disorder, PTSD, PMDD Side Effects:Seizures, suicidal thoughts, serotonin & neuroleptic malignant syndrome Nursing:Monitor for mood changes, suicidal tendencies
Zoloft Generic: Sertraline Category: SSRI Indications:Major depressive disorder,SAD, panic disorder, PTSD, PMDD Side Effects:Seizures, suicidal thoughts, serotonin & neuroleptic malignant syndrome Nursing:Monitor for mood changes, suicidal tendencies
Cymbalta Generic: Duloxetine Category: SNRI Indications:Major depressive disorder, GAD, fibromyalgia, peripheral neuropathic pain Side Effects:Seizures, suicidal thoughts, serotonin, SJ and neuroleptic mal. syn, erthyema multiforme Nursing: Rash,suicidal thoug
Celexa Generic: Citalopram Category: SSRI Indications:Depression. Unlabeled for PMDD, GAD, SAD, OCD, panic disorder, PTSD Side Effects:Suicidal thoughts, serotonin & neuro. malig. syndrome, Torsade de Pointes Nursing:Assess for mood changes,suicidal tenden
Proloxin Generic: Fluphenazine Category: Antipsychotic Route and dose: For HCI form PO: 0.5-10 mg/day (max: 40mg daily) IM: 1.25-2.5 mg 6-8 hrs SE: Extrapyramidal reactions, NMS, sedation, blurred vision, confusion, photosensitivity. MOA: Alters effects of dop
Haldol Generic: Haloperidol Route and dose: PO .5-2.0 mg daily IM 2-5 mg q 1-8 hrs IV .5-5 mg q 30 minutes Category: Antipsychotic; Tourette's Syndrome SE: Extrapyramidal reactions, blurred vision, confusion, drowsiness, wt gain, neuroleptic malignant syndr
Thorazine Generic: Chlorpromazine Route and dose: Psychosis 10-25 mg 2-4 daily Atimedtic: 10-25 mg q 4 hrs Category: Antipsychotic, Antimetic SE: NMS, sedation, blurred vision, confusion, photosensitivity MOA: Alters affects of dopamine in CNS. Alpha adrenergic
Zyprexa Generic: Olanzapine, Rt & dose: PO 5-10 mg/day, target dose 10 mg/day, not to exceed 20 mg/day, IM 5-10 mg Category: Antipsychotic, mood stabilizer MOA: Antagonized dopamine and serotonin type 2 in the CNS. SE: neuroleptic malignant syndrome, seiz
Clozaril Generic: Clozapine, Rt & dose: PO 25 mg/day, target:300-450 mg/day, no more than 900 mg/day MOA: Binds to dopamine receptors in the CNS. SE: neuroleptic malignant syndrome, cardiac arrest, myocarditis, torsades, vent arrhythmias, agranulocytosis, leukop
Geodon Generic: Ziprasidone, Rt & dose: PO 20 mg bid, IM 10 mg q 2 hr, up to 40 mg/day MOA: Prob mediated by antagonism of dopamine type 2 & serotonin type 2 SE: neuroleptic malignant syndrome, prolonged QT, agranulocytosis
Created by: bhuacon