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Pharmacology for Nurses

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Question
Answer
Antiemetic: Emetic response is caused by activation of the ___center in the ___ oblongata.   vomiting; medulla  
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Antiemetic: drugs act on ___ to produce the anti-emetic effect   receptor  
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Serotonin Receptor Anatagonist:   Ondansetron (Zofran)  
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Ondansetron (Zofran): highly effective in treating-chemo-induced nausea ____; ____ and vomiting caused by radiation and anethesia   vomiting; nausea  
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Ondansetron (Zofran): more effective when combined with _____   dexamethasone  
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Ondansetron (Zofran): side effects include _____, diarrhea, and ____   headache; dizziness  
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Ondansetron (Zofran): can be given ___ or IV   PO  
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Dopamine Antagonists:   Prochlorperazine (Compazine)  
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Dopamine Antagonists: Prochlorperazine (Compazine): used for emesis induced by surgery, chemo, and ____   toxins  
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Dopamine Antagonists: Prochlorperazine (Compazine): side effects include anticholinergic effect, hypertension, and ____   sedation  
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Dopamine Antagonists: Methoclopramide (Reglan): used for ____ nausea and vomiting; nausea and vomiting caused by chemo, opioids, toxins, and radiations   postop  
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Cannabinoids: Dronabinol (Marinol) {last resort drug}   Dronabinol (Marinol) {last resort drug}  
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Cannabinoids: Dronabinol (Marinol): used to suppress CINV and for stimulating appetite in patients with ____   AIDS  
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Cannabinoids: Dronabinol (Marinol): watch for dysphoria, CNS effects, tachycardia, hypotension, and _____   drowiness  
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Cannabinoids: Dronabinol (Marinol): Do not combine with other ___ depressants   CNS  
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Other anti-emetic considerations: Glucocorticoids, benesodiazepines, and neurokinin antagonists are also use to treat ____   Nausea and vomiting  
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Motion Sickness: Scopolamine (Transderm Scop-patch): muscarinic antagonist and treats/ prevents motion sickness by acting on vestibular apparatus of ______; side effects include dry mouth, blurred vision , drowiness   inner ear  
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Motion Sickness: Dimenhydrinate (Dramamine)& meclizine (Antivert): antihistamines that affect the _______ pathway to the vomiting center; side effects are ____, dry mouth, blurred vision, urinary retention, and _____   inner ear; sedation; constipation  
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Anti-diarrheal agents: watch for ___ and ___ depletion in these patients; identify the underlying ___ of the diarrhea and treat that first   dehydration; electrolytes; disease  
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Non-Specific Anti-Diarrheal Agents: Opioid-> Diphenoxylate(lomotil): Activates ___receptors in GI tract and ____intestinal transit; causes increased absorption of ___ and ___; is given with ___ to discourage abuse, yet euphoria can occur at high doses   opioids; slows; fluid; nutrients; atropine  
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Opioids-> Loperamide (Imodium): used to ____ discharge in ileostomies; given in capsule form and does not cross the BBB   reduce  
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