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Ch.80 Other GI Drugs

Pharmacology for Nurses

Antiemetic: Emetic response is caused by activation of the ___center in the ___ oblongata. vomiting; medulla
Antiemetic: drugs act on ___ to produce the anti-emetic effect receptor
Serotonin Receptor Anatagonist: Ondansetron (Zofran)
Ondansetron (Zofran): highly effective in treating-chemo-induced nausea ____; ____ and vomiting caused by radiation and anethesia vomiting; nausea
Ondansetron (Zofran): more effective when combined with _____ dexamethasone
Ondansetron (Zofran): side effects include _____, diarrhea, and ____ headache; dizziness
Ondansetron (Zofran): can be given ___ or IV PO
Dopamine Antagonists: Prochlorperazine (Compazine)
Dopamine Antagonists: Prochlorperazine (Compazine): used for emesis induced by surgery, chemo, and ____ toxins
Dopamine Antagonists: Prochlorperazine (Compazine): side effects include anticholinergic effect, hypertension, and ____ sedation
Dopamine Antagonists: Methoclopramide (Reglan): used for ____ nausea and vomiting; nausea and vomiting caused by chemo, opioids, toxins, and radiations postop
Cannabinoids: Dronabinol (Marinol) {last resort drug} Dronabinol (Marinol) {last resort drug}
Cannabinoids: Dronabinol (Marinol): used to suppress CINV and for stimulating appetite in patients with ____ AIDS
Cannabinoids: Dronabinol (Marinol): watch for dysphoria, CNS effects, tachycardia, hypotension, and _____ drowiness
Cannabinoids: Dronabinol (Marinol): Do not combine with other ___ depressants CNS
Other anti-emetic considerations: Glucocorticoids, benesodiazepines, and neurokinin antagonists are also use to treat ____ Nausea and vomiting
Motion Sickness: Scopolamine (Transderm Scop-patch): muscarinic antagonist and treats/ prevents motion sickness by acting on vestibular apparatus of ______; side effects include dry mouth, blurred vision , drowiness inner ear
Motion Sickness: Dimenhydrinate (Dramamine)& meclizine (Antivert): antihistamines that affect the _______ pathway to the vomiting center; side effects are ____, dry mouth, blurred vision, urinary retention, and _____ inner ear; sedation; constipation
Anti-diarrheal agents: watch for ___ and ___ depletion in these patients; identify the underlying ___ of the diarrhea and treat that first dehydration; electrolytes; disease
Non-Specific Anti-Diarrheal Agents: Opioid-> Diphenoxylate(lomotil): Activates ___receptors in GI tract and ____intestinal transit; causes increased absorption of ___ and ___; is given with ___ to discourage abuse, yet euphoria can occur at high doses opioids; slows; fluid; nutrients; atropine
Opioids-> Loperamide (Imodium): used to ____ discharge in ileostomies; given in capsule form and does not cross the BBB reduce
Created by: emv2435