Pharmacology for Nurses
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| Suppress Preterm Labor Drugs | On average, tocolytics delay delivery by 24-48 hours
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| Suppress Preterm Labor Drugs | tocolytics + glucocorticoids= better lung development in noenates
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| Terbutaline (Brethine) | Adverse effects include pulmonary edema, hypotension, hyperglycemia in mother and tachycardia in mother and fetus
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| Nifedepine (Procardia, Adalat, Nifedical) | Can suppress preterm labor for 24-28 hours; calcium channel blocker
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| Indomethacin (indocin) | Cyclooxygenase inhibitor; suppresses preterm labor
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| Hydroxyprogesterone caproate (Makena) | Prevents preterm labor; used in women with single baby pregnancy; IM injection begin at 16-20 weeks gestation and continues to 36 weeks or delivery
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| Antobiotics (clindamycin PO or vaginal) | if administered with bacterial vaginosis, it reduced the preterm delivery rate by 6%
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| Prostaglandins: Dinoprostone (cervidil, prepidil) | Cervical ripening and induction of labor drugs; acts activating collagen that breaks down the collagen network on the cervix and causes it to soften
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| Oxytocin (pitocin) | Carefule to watch for uterine rupture especially after multiple pregnancies; must monitor BP, HR, and uterine contraction in mother and fetal heart rate in fetus
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| Tranexamic acid (lysteda) | Drug for Menorrhagia: acts by inhibiting plasmin thereby decreasing the amount of bleeding; used for heavy menstrual bleeding and for trauma patients with hemorrhage
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