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Ch. 64 Uterine Funct

Pharmacology for Nurses

Suppress Preterm Labor Drugs On average, tocolytics delay delivery by 24-48 hours
Suppress Preterm Labor Drugs tocolytics + glucocorticoids= better lung development in noenates
Terbutaline (Brethine) Adverse effects include pulmonary edema, hypotension, hyperglycemia in mother and tachycardia in mother and fetus
Nifedepine (Procardia, Adalat, Nifedical) Can suppress preterm labor for 24-28 hours; calcium channel blocker
Indomethacin (indocin) Cyclooxygenase inhibitor; suppresses preterm labor
Hydroxyprogesterone caproate (Makena) Prevents preterm labor; used in women with single baby pregnancy; IM injection begin at 16-20 weeks gestation and continues to 36 weeks or delivery
Antobiotics (clindamycin PO or vaginal) if administered with bacterial vaginosis, it reduced the preterm delivery rate by 6%
Prostaglandins: Dinoprostone (cervidil, prepidil) Cervical ripening and induction of labor drugs; acts activating collagen that breaks down the collagen network on the cervix and causes it to soften
Oxytocin (pitocin) Carefule to watch for uterine rupture especially after multiple pregnancies; must monitor BP, HR, and uterine contraction in mother and fetal heart rate in fetus
Tranexamic acid (lysteda) Drug for Menorrhagia: acts by inhibiting plasmin thereby decreasing the amount of bleeding; used for heavy menstrual bleeding and for trauma patients with hemorrhage
Created by: emv2435