Pharmacology for Nurses
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Drugs for Migraines | Migraines are though to be caused by intracranial blood vessel dilation and inflammation and is associated with nausea, vomiting, photophobia, and phonophobia
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Drugs for Migraines | Triggers for migraines: emotions, food, caffeine, weather
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Ergotamine (Ergostat) | drug commonly coupled with caffeine to enhance vasoconstriction and absorption
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Ergotamine (Ergostat): Drug Interactions | Should not be used to triptans (sumatriptan, zolmitriptain) due to prolonged vessel effects
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Ergotamine (Ergostat): Drug Interactions | Watch for interaction with other CYP450 inhibitors because it can cause toxic dose of ergotamine
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Serotonin Receptor Agonists: Saumatriptan (Imitrex) | Is considered the BEST drug for migraine attacks
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Serotonin Receptor Agonists: Saumatriptan (Imitrex): Drug interactions | Avoid use with ergotamine and MAOIs in the last 224 hours
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Migraine Preventive Therapy: Beta Blockers: Propranolol (Inderal) | Used most often to prevent migraines
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Migraine Preventive Therapy: Beta Blockers: Propranolol (Inderal) | Used to decrease number and intensity of migraines
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