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Ch.30 Migraine Drugs

Pharmacology for Nurses

Drugs for Migraines Migraines are though to be caused by intracranial blood vessel dilation and inflammation and is associated with nausea, vomiting, photophobia, and phonophobia
Drugs for Migraines Triggers for migraines: emotions, food, caffeine, weather
Ergotamine (Ergostat) drug commonly coupled with caffeine to enhance vasoconstriction and absorption
Ergotamine (Ergostat): Drug Interactions Should not be used to triptans (sumatriptan, zolmitriptain) due to prolonged vessel effects
Ergotamine (Ergostat): Drug Interactions Watch for interaction with other CYP450 inhibitors because it can cause toxic dose of ergotamine
Serotonin Receptor Agonists: Saumatriptan (Imitrex) Is considered the BEST drug for migraine attacks
Serotonin Receptor Agonists: Saumatriptan (Imitrex): Drug interactions Avoid use with ergotamine and MAOIs in the last 224 hours
Migraine Preventive Therapy: Beta Blockers: Propranolol (Inderal) Used most often to prevent migraines
Migraine Preventive Therapy: Beta Blockers: Propranolol (Inderal) Used to decrease number and intensity of migraines
Created by: emv2435