Microbiology VII
Help!
|
|
||||
|---|---|---|---|---|---|
| What causes typhoid fever vs typhus? | Typhoid fever: bacteria= Salmonella typhi typhus: bacteria=Rockettsia prowaseklii (epidemic), tphi (endemic), tsutsugamushi (scrub typhus)
🗑
|
||||
| What is a naked icosahedral viral structure? | just nucelocapsid and genome
🗑
|
||||
| What is an enveloped icosahedral viral structure? | surface protein with lipid bilayer, capdis, and genome
🗑
|
||||
| What is an enveloped helical viral structure? | surface protein, matrix or core protein, lipid bilayer, and nucleocapsid and genome
🗑
|
||||
| What is viral recombination? | exchange of genes b/w 2 chr by crossing over in regions with base pair homology
🗑
|
||||
| What is viral reassortment? | viruses with segmented genomes (like influenza) exhange segments, causes pandemics
🗑
|
||||
| What is viral complementation? | 1 of 2 viruses invade cell with nonfunctional mutation, non mutated will complement mutated and make normal protein for both
🗑
|
||||
| What is viral phenotypic mixing? | infection of cell with 2 viruses, virus A can be coated by surface protein of virus B. So B will determine infectivity, but genome is still A
🗑
|
||||
| What is a live attenuated viral vaccine, do they need a booster? Who should not get them | induce both humoral and cell mediated immunity. can revert on occassion. no booster. dangerous to give to ICPt and their close contacts
🗑
|
||||
| What type of immunity can a killed virus ellicit? | only humoral, so might need booster
🗑
|
||||
| What viruses have live attenuated vaccines? | small pox, yellow fever, chicken pox, Sabin's polio virus, MMR
🗑
|
||||
| What is a mnomonic for the live attenuated vaccines? | LIVE! See SMALL YELLOW CHICKENS get vaccinated with SABIN's and MMR!
🗑
|
||||
| Which viruses have a killed virus vaccine? | Rabies, Influenza, Salk Polio, HAV vaccine
🗑
|
||||
| What is a mnonic for the killed virus vaccines? | salK=killed. RIP Always. Rabies, Influenza, Salk Polio, HAV
🗑
|
||||
| What are 2 viral recombinant vaccines? | HBV (HBsAg, HPV (6,11,16,18)
🗑
|
||||
| What is the only DNA virus with ssDNA? | parvovirus
🗑
|
||||
| Wich 3 DNA viral genomes are non linear? | pailloma, polyoma, hepadnavirus (circular)
🗑
|
||||
| What is the only dsRNA virus? | reoviridae
🗑
|
||||
| What are 7 positive ssRNA viruses? | Retrovirus, Togavirus, flavivirus, Coronavirus, Hepevirus,calicivirus, picronavirus
🗑
|
||||
| What is the mnemonic for the +ssRNA viruses? | I went to a RETRO TOGA party where I drank FLAVored CORONA and ate HIPPY CALifornia PICKLES
🗑
|
||||
| Which types of viruses have genomes which are infectious on their own? | dsDNA viruses (except poxvirus, HBV) and +ssRNA are infectious. -ssRNA and dsRNA arent
🗑
|
||||
| What is the only diploid virus family? | retroviruses, 2 identical ssRNA molecules
🗑
|
||||
| Where do DNA viruses replicate? What is the exception? | nucleus, except poxvirus
🗑
|
||||
| Where do RNA viruses duplicate? What is the exception? | cytoplasm, except influenza and retroviruses
🗑
|
||||
| what are 7 naked viruses? | Calcivirus, Picronavirus, Reovirus, Parvovirus, adenovirus, Papilloma, Polyoma virus
🗑
|
||||
| What is a mnemonic for the naked viruses? | Naked CPR and PAPP smear (DNA=PAPP RNA=CPR)
🗑
|
||||
| Where do enveloped viruses get their envelope? What is the exception? | usually plasma membrane when they leave. Except herpesvirus which gets it from the nuclear membrane
🗑
|
||||
| What are 7 DNA viruses? | Hepadna, Herpes, Adeno, Pox, Parvo, Papilloma, Polyoma
🗑
|
||||
| What is a mnemonic for the DNA viruses? | HHAPPPPy
🗑
|
||||
| What are the general charactersitics of DNA viruses? | 1.ds 2. linear 3. icosahedral 4. replicate in nuclease
🗑
|
||||
| Which virus is the exception to the rule that DNA viruses are ds and linear? | Parvovirus is single stranded. papilloma and polyoma( supercoiled) and hepadna (circular and incomplete) do not have linear genomes
🗑
|
||||
| What is the exception to the rule that all DNA viruses are icosahedral and replicate in the nucleus? | Pox virus has a complex shape and carries its own DNA dependent RNA pol
🗑
|
||||
| What is the envelope and DNA structure of the Herpesvirus family? | has an envelope, dsDNA
🗑
|
||||
| What does HSV-1 cause? (3) | oral (and some genital) lesions, spontaneous temporal lobe encephalitis, keratoconjunctivitis
🗑
|
||||
| What does HSV-2 cause? | genital (some oral) lesions
🗑
|
||||
| What does VZV (HHV-3) cause? | chickenpox, zoster(shingles)
🗑
|
||||
| What diesease does EBV(HHV-4) cause? (3) | mononuceloisis, Burkitt's lymphoma, Hodgkin's lymphoma
🗑
|
||||
| What disease does CMV (HHV-5) cause? | infects IcPT(espAIDS retinitis), transplant recipient, congenital defectos (SIGHT-omegalovirus)
🗑
|
||||
| What does HHV-6 cause? | roseola (exathem subitum)
🗑
|
||||
| What does HHV-8 (KSHV) cause? | Kaposi's sarcoma
🗑
|
||||
| What is the enveolpe and DNA structure of Hepadnavirus? | has an envelope, DS but partial circular
🗑
|
||||
| What disease does HBV cause? Is there a vaccine? What is interesting about it's enzymes? | acute or chronic hepatitis, vaccine containes HBV surface Ag. has reverse trancriptase
🗑
|
||||
| What is the enveope and genome of adenovirus? | Non enveloped linear dsDNA
🗑
|
||||
| What 3 diseases does adenovirus cause? | febrile pharyngitis (ST, acutue hemorragic cystitis), pneumonia, conjunctivitis- pink eye(watery)
🗑
|
||||
| What is the envelope and genome structure of parvovirus? | no envelope. ss linear (-) DNA. smallest DNA virus
🗑
|
||||
| What diesease does parvovirus like B19 virus cause? | aplastic crises in SCA, slapped cheek rash in children-5th disese, RBC destructuion in fetus causing hydrops fetalis, pure RBC aplasia and RA in adults
🗑
|
||||
| What are the enveope and genome characterisitcs of papillomavirus? | no envelope, dsDNA circular
🗑
|
||||
| What does HPV 1,2,6,11 cause? | warts
🗑
|
||||
| What does HPV 16, 18 cause? | CIN, cervical cancer
🗑
|
||||
| What HPV strains is there a vaccine for? | 16, 18
🗑
|
||||
| What are the envelope and genome characterisitics of polyomavirus? | no envelope. dsDNA circular
🗑
|
||||
| What does JC polyomavirus cause? Who gets it? | progressive multifocal leukoencephalopathy (PML) in HIV
🗑
|
||||
| What does BK polyomavirus cause? who gets it? | targets kidney in transplant pt
🗑
|
||||
| What is the envelope and genome of Pox virus? | enveloped dsDNA linear virus. largest
🗑
|
||||
| What does vaccina poxvirus cause? | cow pox, milkmaids blisters
🗑
|
||||
| What is molluscum contagiosum and what virus family causes it? | fleshcolored dome lesions with central dimple. caused by pox family of viruses
🗑
|
||||
| Where is HSV-1 found latent? what disease does it cause? | trigeminal ganglia. causes gingivostomatitis, keratoconjunctivits, temporal lobe encephalitis. herpes labialis
🗑
|
||||
| How is HSV-1 transmitted? | secretions or saliva
🗑
|
||||
| What does HSV-2 cause and where is it latent? | causes genital herpes, neonatal herpes. latent in sacral ganglia
🗑
|
||||
| How is HSV-2 spread? | sexual contact, perinatal
🗑
|
||||
| What disease does VZV cause? where does it go latent? | varicella zoster ( chicken pox/shingles). latent in dorsal root or trigeminal ganglia)
🗑
|
||||
| What does EBV cause? Where does it go latent? | cuases infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma. Latent in B cells
🗑
|
||||
| How is VZV spread? | respiratory secretions
🗑
|
||||
| How is EBV spead? | saliva, respiratory secretions
🗑
|
||||
| What does CMV cause, where does it go latent? | congetina linfection (negative monospot), pneumonia, retinitis. latent in mononiuclear cells
🗑
|
||||
| What is characteristic of a cell infected with CMV? | owl's eye inclusions
🗑
|
||||
| How is CMV spread? | congential, transfusion, sexual contact, saliva, urine, transplant
🗑
|
||||
| high fevers for several days that can cause seizures. followed by diffues macular rash. esp in kids. Pathogen? | Roseola. likely HHV-6
🗑
|
||||
| How is HHV-8 spread, what does it cause? | spread by sexual contact. causes Kaposi's sarcoma
🗑
|
||||
| What is a Tzanck test and what pathogens does it assay for? What else might be seen? | smear of opened skin vesicle to lok for multinucleated giant cells. Assay for HSV-1, HSV-2, VZV. Cells will also have intra nuclear Cowdry A inclusions
🗑
|
||||
| What is a mnomonic for the things detected by a Tzanck test? | Tzanck heavens I dont have herpes
🗑
|
||||
| 15-20 yr old, characterized by fever, hepatosplenomegaly, pharyngitis, lymphadenopathy. Pathogen? what might be seen on a peripheral blood smear? | EBV. atypical lymphocytes are not infected B cells but rather reactive cytotoxic T cells
🗑
|
||||
| What is a monospot test? what does it mean if positive? | detects EBV via agglutination of sheep or horse RBCs. so can be positive with Burkitt's and Hodgkins lymphoma and nasopharyngeal carcinoma.
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
tjs2123
Popular USMLE sets