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Autacoid Drugs

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Question
Answer
Histamine receptors   H1, H2, H3  
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H1 receptors   allergic reactions  
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Which receptor causes dermatitis, rhinitis, conjunctivitis?   H1 receptors  
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What happens if H1 receptors in the skin and mucous membrane are activated?   cause vasodilation,increases vascular permeability, and leads to erythema (heat and redness), congestion, edema and inflammation.  
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What are H2 receptors involved in?   increase gastric acid secretion, and cause allergic reactions  
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What happens if H2 receptors in the heart are activated?   increases the heart rate and contractility  
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what happens if H3 receptors are activated?   inhibit the release of histamine and other neurotransmitters  
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antihistamines   histamine receptor antagonists, H1, H2 receptor antagonists  
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Which generation of H1 receptor antagonist is preffered in treating allergies? why?   The second generation is preffered because it causes little or no sedation.  
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