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Pharm Chap 26
Autacoid Drugs
Question | Answer |
---|---|
Histamine receptors | H1, H2, H3 |
H1 receptors | allergic reactions |
Which receptor causes dermatitis, rhinitis, conjunctivitis? | H1 receptors |
What happens if H1 receptors in the skin and mucous membrane are activated? | cause vasodilation,increases vascular permeability, and leads to erythema (heat and redness), congestion, edema and inflammation. |
What are H2 receptors involved in? | increase gastric acid secretion, and cause allergic reactions |
What happens if H2 receptors in the heart are activated? | increases the heart rate and contractility |
what happens if H3 receptors are activated? | inhibit the release of histamine and other neurotransmitters |
antihistamines | histamine receptor antagonists, H1, H2 receptor antagonists |
Which generation of H1 receptor antagonist is preffered in treating allergies? why? | The second generation is preffered because it causes little or no sedation. |