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Drugs recognition: chap 14

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
quinidine   Sodium Channel Blockers clasee IA  
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lidocaine (Xylocaine)   Sodium Channel Blockers class IB  
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flecainide (Tambacor)   Sodium Channel Blockers IC  
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propafenone (Rythmol)   Sodium Channel Blockers IC  
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esmolol (Brevibloc)   Beta Blockers  
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metoprolol (Lopressor, Toprol XL)   Beta Blockers  
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propranolol (Inderal)   Beta Blockers  
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sotalol (Betapace)   nonselective Beta Blockers Class III  
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amiodarone (Cordarone, Pacerone)   Potassium Channel Blockers  
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dofetilide (Tikosyn)   Potassium Channel Blockers restricted access in US  
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diltiazem (Cardizem, Diltia)   Calcium channel Blockers class IV  
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verapamil (Verelan, Calan)   Calcium Blockers Class IV  
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digoxin (Lanoxin)   Miscellaneous  
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magnesium   Miscellaneous  
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quinidine   Diarrhea, syncope, thrombocytopenia, neuro symptoms  
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what dose class IA do?   Decrease conduction velocity Prolong ventricular action  
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lidocaine indication sodium IB   V-tach Ventricular arrhythmias  
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lidocaine side effects   CNS (nervousness, tremor, paresthesia), cardiac arrest  
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flecaine indication   supreventricular and ventricular arrhymias  
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flecaine side effects   Reentrant v-tach, bronchospasm, hematologic abnormalities (leukopenia, thrombocytopenia) seizures  
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propafenone indication   Ventricular arrhythmias  
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propafenone adverse effects   ventricular arrhythmias, hematologic abnormalities (agranulocytosis, anemia, thrombocytopenia)  
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Atrial fib & flutter   Control ventricular rate: BB, CCB, & digoxin AND anticoagulant Cardioversion & Class I or Class II drugs  
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magnesium sulfate   drug-induced arrhythmias, preeclampsia, hypomagnesemia  
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diltiazem (Cardizem)** verapamil (Calan)** indication   Acute SVT & atrial fib  
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verapamil, diltiazem adverse effects   Exacerbate ventricular arrhythmias  
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sotalol indications   atrial & ventricular arrhythmias  
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sotalol adverse effects   arrhythmias, bronchospasm  
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dofetilide adverse effect   life-threatening arrhythmias  
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dofetilide indication   Atrial fib/flutter  
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dofetilide administration   monitor EKG  
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amiodarone adverse effects   Reversible cardiac effects Corneal micro-deposits Hypothyroidism Neuropathy Pulmonary fibrosis  
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amiodarone indications   Suppress SV & ventricular arrhythmias, atrial fib & flutter, SV & ventricular tachycardia  
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metoprolol, propanolol indication   SV & ventricular arrhythmias MI – protect heart against damage  
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esmolol indication   Acute SV tachycardia & HTN IV  
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treatment of Torsades de pointes   withdrawal of the causative agent, correction of any electrolyte abnormalities such as hypokalemia, IV administration of magnesium sulfate, cardiac over-drive pacing, IV administration of isoproterenol (B adrenoceptor agonist => shortening the QT interval  
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causes of Torsades de pointes   polymorphic ventricular tachycardia, drug-induced (prolong the QT interval)  
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