Drugs recognition: chap 14
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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quinidine | Sodium Channel Blockers clasee IA
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lidocaine (Xylocaine) | Sodium Channel Blockers class IB
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flecainide (Tambacor) | Sodium Channel Blockers IC
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propafenone (Rythmol) | Sodium Channel Blockers IC
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esmolol (Brevibloc) | Beta Blockers
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metoprolol (Lopressor, Toprol XL) | Beta Blockers
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propranolol (Inderal) | Beta Blockers
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sotalol (Betapace) | nonselective Beta Blockers Class III
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amiodarone (Cordarone, Pacerone) | Potassium Channel Blockers
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dofetilide (Tikosyn) | Potassium Channel Blockers
restricted access in US
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diltiazem (Cardizem, Diltia) | Calcium channel Blockers class IV
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verapamil (Verelan, Calan) | Calcium Blockers Class IV
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digoxin (Lanoxin) | Miscellaneous
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magnesium | Miscellaneous
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quinidine | Diarrhea, syncope, thrombocytopenia, neuro symptoms
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what dose class IA do? | Decrease conduction velocity
Prolong ventricular action
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lidocaine indication sodium IB | V-tach
Ventricular arrhythmias
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lidocaine side effects | CNS (nervousness, tremor, paresthesia), cardiac arrest
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flecaine indication | supreventricular and ventricular arrhymias
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flecaine side effects | Reentrant v-tach, bronchospasm, hematologic abnormalities (leukopenia, thrombocytopenia) seizures
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propafenone indication | Ventricular arrhythmias
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propafenone adverse effects | ventricular arrhythmias, hematologic abnormalities (agranulocytosis, anemia, thrombocytopenia)
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Atrial fib & flutter | Control ventricular rate: BB, CCB, & digoxin AND anticoagulant
Cardioversion & Class I or Class II drugs
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magnesium sulfate | drug-induced arrhythmias, preeclampsia, hypomagnesemia
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diltiazem (Cardizem)** verapamil (Calan)** indication | Acute SVT & atrial fib
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verapamil, diltiazem adverse effects | Exacerbate ventricular arrhythmias
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sotalol indications | atrial & ventricular arrhythmias
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sotalol adverse effects | arrhythmias, bronchospasm
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dofetilide adverse effect | life-threatening arrhythmias
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dofetilide indication | Atrial fib/flutter
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dofetilide administration | monitor EKG
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amiodarone adverse effects | Reversible cardiac effects
Corneal micro-deposits
Hypothyroidism
Neuropathy
Pulmonary fibrosis
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amiodarone indications | Suppress SV & ventricular arrhythmias, atrial fib & flutter, SV & ventricular tachycardia
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metoprolol, propanolol indication | SV & ventricular arrhythmias
MI – protect heart against damage
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esmolol indication | Acute SV tachycardia & HTN
IV
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treatment of Torsades de pointes | withdrawal of the causative agent, correction of any electrolyte abnormalities such as hypokalemia, IV administration of magnesium sulfate, cardiac over-drive pacing, IV administration of isoproterenol (B adrenoceptor agonist => shortening the QT interval
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causes of Torsades de pointes | polymorphic ventricular tachycardia, drug-induced (prolong the QT interval)
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