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Antiarrhythmics
Drugs recognition: chap 14
| Question | Answer |
|---|---|
| quinidine | Sodium Channel Blockers clasee IA |
| lidocaine (Xylocaine) | Sodium Channel Blockers class IB |
| flecainide (Tambacor) | Sodium Channel Blockers IC |
| propafenone (Rythmol) | Sodium Channel Blockers IC |
| esmolol (Brevibloc) | Beta Blockers |
| metoprolol (Lopressor, Toprol XL) | Beta Blockers |
| propranolol (Inderal) | Beta Blockers |
| sotalol (Betapace) | nonselective Beta Blockers Class III |
| amiodarone (Cordarone, Pacerone) | Potassium Channel Blockers |
| dofetilide (Tikosyn) | Potassium Channel Blockers restricted access in US |
| diltiazem (Cardizem, Diltia) | Calcium channel Blockers class IV |
| verapamil (Verelan, Calan) | Calcium Blockers Class IV |
| digoxin (Lanoxin) | Miscellaneous |
| magnesium | Miscellaneous |
| quinidine | Diarrhea, syncope, thrombocytopenia, neuro symptoms |
| what dose class IA do? | Decrease conduction velocity Prolong ventricular action |
| lidocaine indication sodium IB | V-tach Ventricular arrhythmias |
| lidocaine side effects | CNS (nervousness, tremor, paresthesia), cardiac arrest |
| flecaine indication | supreventricular and ventricular arrhymias |
| flecaine side effects | Reentrant v-tach, bronchospasm, hematologic abnormalities (leukopenia, thrombocytopenia) seizures |
| propafenone indication | Ventricular arrhythmias |
| propafenone adverse effects | ventricular arrhythmias, hematologic abnormalities (agranulocytosis, anemia, thrombocytopenia) |
| Atrial fib & flutter | Control ventricular rate: BB, CCB, & digoxin AND anticoagulant Cardioversion & Class I or Class II drugs |
| magnesium sulfate | drug-induced arrhythmias, preeclampsia, hypomagnesemia |
| diltiazem (Cardizem)** verapamil (Calan)** indication | Acute SVT & atrial fib |
| verapamil, diltiazem adverse effects | Exacerbate ventricular arrhythmias |
| sotalol indications | atrial & ventricular arrhythmias |
| sotalol adverse effects | arrhythmias, bronchospasm |
| dofetilide adverse effect | life-threatening arrhythmias |
| dofetilide indication | Atrial fib/flutter |
| dofetilide administration | monitor EKG |
| amiodarone adverse effects | Reversible cardiac effects Corneal micro-deposits Hypothyroidism Neuropathy Pulmonary fibrosis |
| amiodarone indications | Suppress SV & ventricular arrhythmias, atrial fib & flutter, SV & ventricular tachycardia |
| metoprolol, propanolol indication | SV & ventricular arrhythmias MI – protect heart against damage |
| esmolol indication | Acute SV tachycardia & HTN IV |
| treatment of Torsades de pointes | withdrawal of the causative agent, correction of any electrolyte abnormalities such as hypokalemia, IV administration of magnesium sulfate, cardiac over-drive pacing, IV administration of isoproterenol (B adrenoceptor agonist => shortening the QT interval |
| causes of Torsades de pointes | polymorphic ventricular tachycardia, drug-induced (prolong the QT interval) |
Created by:
prinluu
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