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Drugs recognition: chap 12

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
digoxin (Lanoxin)   Positive Inotropic (increases strength of contraction)  
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digoxin immune Fab – antidote for digoxin toxicity   Positive Inotropic (increases strength of contraction)  
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ACE inh   Vasodilators  
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ARB’s   Vasodilators  
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hydralazine (Apresoline)   Vasodilators  
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isorobide dinitrate (Isordil)   Vasodilators  
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spironolactone (Aldactone)   Aldosterone Antagonists  
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eplerenone (Inspra)   Aldosterone Antagonists  
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carvedilol (Coreg)   Beta Blockers  
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metoprolol (Lopressor, Toprol XL)   Beta Blockers  
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bisoprolol (Zebeta)   Beta Blockers  
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furosemide (Lasix)   Diuretics  
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bumetanide (Bumex)   Diuretics  
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torsemide (Demadex)   Diuretics  
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bumetamide   reduce edema and congestion  
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furosemide   reduce edema and congestion  
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torsemide   reduce edema and congestion  
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what lead to cardiac remodeling   angiotensin II and sympathetic activation  
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what does cardiac remodeling do   reduce systolic and diastolic function  
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what do drugs of positive inotropic do?   increase cardiac output by increasing cardiac contractility  
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drugs used to prevent cardiac remodeling   angiotensin inhibitors and B- blockers  
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digitalis absorption inhibited by   antacids and cholestyramide  
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digitalis clearance reduced by   diltiazem, verapamil, and quinidine  
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diuretic-induced hypokalemia   precipitates (worsen) digitalis toxicity  
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carvedilol indication   heart failure  
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carvedilol adverse effects   light-headedness, dizziness, bradycardia, worsening of heart failure (vasodilation, and decreased blood pressure)  
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carvedilol class   block a and b- adrenoceptor, antioxidant  
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B-blockers moa   Reduce excess sympathetic stimulation  
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Aldosterone Blockers moa   Increase Na excretion, decrease K excretion, mild diuresis  
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Aldosterone Blockers adverse actions   Hyperkalemia,Gynecomastia,Impotence  
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a pt complaining of nausea, vomiting, blurred, abnormal-colored vision, and palpitations   adverse effects of digoxin  
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positive inotropic   increase contractility  
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