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Heart Failure
Drugs recognition: chap 12
| Question | Answer |
|---|---|
| digoxin (Lanoxin) | Positive Inotropic (increases strength of contraction) |
| digoxin immune Fab – antidote for digoxin toxicity | Positive Inotropic (increases strength of contraction) |
| ACE inh | Vasodilators |
| ARB’s | Vasodilators |
| hydralazine (Apresoline) | Vasodilators |
| isorobide dinitrate (Isordil) | Vasodilators |
| spironolactone (Aldactone) | Aldosterone Antagonists |
| eplerenone (Inspra) | Aldosterone Antagonists |
| carvedilol (Coreg) | Beta Blockers |
| metoprolol (Lopressor, Toprol XL) | Beta Blockers |
| bisoprolol (Zebeta) | Beta Blockers |
| furosemide (Lasix) | Diuretics |
| bumetanide (Bumex) | Diuretics |
| torsemide (Demadex) | Diuretics |
| bumetamide | reduce edema and congestion |
| furosemide | reduce edema and congestion |
| torsemide | reduce edema and congestion |
| what lead to cardiac remodeling | angiotensin II and sympathetic activation |
| what does cardiac remodeling do | reduce systolic and diastolic function |
| what do drugs of positive inotropic do? | increase cardiac output by increasing cardiac contractility |
| drugs used to prevent cardiac remodeling | angiotensin inhibitors and B- blockers |
| digitalis absorption inhibited by | antacids and cholestyramide |
| digitalis clearance reduced by | diltiazem, verapamil, and quinidine |
| diuretic-induced hypokalemia | precipitates (worsen) digitalis toxicity |
| carvedilol indication | heart failure |
| carvedilol adverse effects | light-headedness, dizziness, bradycardia, worsening of heart failure (vasodilation, and decreased blood pressure) |
| carvedilol class | block a and b- adrenoceptor, antioxidant |
| B-blockers moa | Reduce excess sympathetic stimulation |
| Aldosterone Blockers moa | Increase Na excretion, decrease K excretion, mild diuresis |
| Aldosterone Blockers adverse actions | Hyperkalemia,Gynecomastia,Impotence |
| a pt complaining of nausea, vomiting, blurred, abnormal-colored vision, and palpitations | adverse effects of digoxin |
| positive inotropic | increase contractility |
Created by:
prinluu
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