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Nurs 330 Test #2

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Question
Answer
What are the Cholinergic Receptor Functions?   Nicotinic-N and Nicotinic-M  
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Where are Nicotinic-N receptors located and what do they do?   All ganglia and adrenal medulla. They stimulate postganglionic nerves and release of Norepinphrine.  
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Whatre are Nicotinic-M receptors located and what do they do?   The neuromuscular junction. They stimulate contraction of the skeletal muscles.  
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What muscarinic response is expected from each of these parasympathetic target organ? Eye, Heart, Lung, Bladder, GI Tract, Sweat Glands, Sex Organs, and Blood Vessels?   Eye: miosis, Heart: ↓ rate, Lung: constrict Bronchi and ↑ secretion, Bladder: voiding, GI Tract: salavation, ↑ secretions,motility and defecation, Sweat Glands: ↑ sweat, Sex Organs: erection, and Blood Vessels: vasodilation  
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What reactions do direct-acting muscarinic agonist have on the body?   All Muscarinic effects: ↓ heart rate ( - chronotropic), ↓ force of contraction ( - inotropic), vasodialation ( ↓ bp), ↑ GI Motility and Secretions, stimulate urine, and miosis.  
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Bethanechol (Urecholine)uses:   Muscarinic agonist Uses: urinary retention--postoperative, postpartum, neurogenic bladder, Paralytic Ileus (postoperative)  
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Bethanechol (Urecholine) Adverse Effects:   Adverse Effects: higher incidence w/ SQ vs. PO--never IV or IM, hypotension, bradycardia, salvation, ↑ GI Acid, Cramps, Diarrhea, and brochoconstriction.  
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Bethanechol (Urecholine) Contraindications:   Intestinal Obstruction or Urinary Tract Obstruction, Asthma, Hyperthyroidism ( ↑ dysrhythmias), peptic ulcer diseas  
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Bethanechol (Urecholine) Nursing Implications:   Observe for therapeutic effects-Urination, Defecation. Teach to take between meals (reduces nausea)  
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Miotics -- Muscarinic Agonists uses:   pupil constriction, treats Glaucoma (reduces intraocular pressure)  
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Adverse effects of miotics:   systemic effects: eye- itching, pain, ciliary spasm, blurred vision (decreased accommodation)  
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Where should a nurse put pressure when administering eye drops?   Lacrimal ducts 1 -2 minutes after eye drops. This will help decrease systemic effects by reducing passage of drops to nasal passages.  
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What is the drug Acetylcholine (Miochol) used for?   Eye drops for miosis. It is a Cholinergic Agent (parasympathomimetic), a muscarinic agonist.  
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