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Nurs 330 Test #2

What are the Cholinergic Receptor Functions? Nicotinic-N and Nicotinic-M
Where are Nicotinic-N receptors located and what do they do? All ganglia and adrenal medulla. They stimulate postganglionic nerves and release of Norepinphrine.
Whatre are Nicotinic-M receptors located and what do they do? The neuromuscular junction. They stimulate contraction of the skeletal muscles.
What muscarinic response is expected from each of these parasympathetic target organ? Eye, Heart, Lung, Bladder, GI Tract, Sweat Glands, Sex Organs, and Blood Vessels? Eye: miosis, Heart: ↓ rate, Lung: constrict Bronchi and ↑ secretion, Bladder: voiding, GI Tract: salavation, ↑ secretions,motility and defecation, Sweat Glands: ↑ sweat, Sex Organs: erection, and Blood Vessels: vasodilation
What reactions do direct-acting muscarinic agonist have on the body? All Muscarinic effects: ↓ heart rate ( - chronotropic), ↓ force of contraction ( - inotropic), vasodialation ( ↓ bp), ↑ GI Motility and Secretions, stimulate urine, and miosis.
Bethanechol (Urecholine)uses: Muscarinic agonist Uses: urinary retention--postoperative, postpartum, neurogenic bladder, Paralytic Ileus (postoperative)
Bethanechol (Urecholine) Adverse Effects: Adverse Effects: higher incidence w/ SQ vs. PO--never IV or IM, hypotension, bradycardia, salvation, ↑ GI Acid, Cramps, Diarrhea, and brochoconstriction.
Bethanechol (Urecholine) Contraindications: Intestinal Obstruction or Urinary Tract Obstruction, Asthma, Hyperthyroidism ( ↑ dysrhythmias), peptic ulcer diseas
Bethanechol (Urecholine) Nursing Implications: Observe for therapeutic effects-Urination, Defecation. Teach to take between meals (reduces nausea)
Miotics -- Muscarinic Agonists uses: pupil constriction, treats Glaucoma (reduces intraocular pressure)
Adverse effects of miotics: systemic effects: eye- itching, pain, ciliary spasm, blurred vision (decreased accommodation)
Where should a nurse put pressure when administering eye drops? Lacrimal ducts 1 -2 minutes after eye drops. This will help decrease systemic effects by reducing passage of drops to nasal passages.
What is the drug Acetylcholine (Miochol) used for? Eye drops for miosis. It is a Cholinergic Agent (parasympathomimetic), a muscarinic agonist.
Created by: ewooda05