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Neuro Pharma

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Created by: blue ducky

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Question	Answer
epinephrine	a-agonist, decrease aqueous humor production, don't use in angle closure because it will cause midriasis
brimonidine	a-agonist, decrease aqueous humor production
timolol	b-blcoker, decrease aqueous humor production
carteolol	b-blcoker, decrease aqueous humor production
betaxolol	b-blcoker, decrease aqueous humor production
acetazolimide	diuretic, decrease aqueous humor production
carbachol	direct cholinomimetic, increase aqueous humor drainage. Miosis
pilocarpine	direct cholinomimetic, increase aqueous humor drainage. Miosis
Echothiophate	indirect cholinomimetic, increase aqueous humor drainage. Miosis
physostigmine	indirect cholinomimetic, increase aqueous humor drainage. Miosis
Latanoprost	Prostaglandin, increase aqueous humor drainage, darkins pupul
Morphine	opiod analgesic also used IV as general anesthesia.
Methadone	opiod analgesic, pulm edema and drug addiction
Meperidine	opiod analgesic
Fentanyl	opioid analgesic also used iv as general anesthetia
Codeine	opioid analgesic
Heroin	opioid analgesic
Dextromethorphan	opioid analgesic, pain and cough
Diphenoxylate	opioid analgesic, diarrhea
Naloxone	opiod antagonist
Naltrexone	opioid antagonist
Butorphanol	partial mu and kappa opiod agonist, causes less resp depression but used for pain.
Tramadol	weak opioid agonist, many neurotranmitters, decreases seizure threshold
Phenytoin	epilepsy nystagmus, dilopia, ataxia, sedation, gingival hyperplasia, hirsutism, megaloblastic anemia, teratogenesis, SLE-like sx, CP450
Carbamazepine	epilepsy Diplopia, ataxa, blood dyscrasia, lover toxic, teratogen, CP450, SIADH, stevens-johnson syndrome
Lamotrigine	epilepsy stevens-johnson syndrome
GABApentin	epilepsy sedation, ataxia
Topiramate	epilepsy sedatio, mental dulling, kidney stones, weight loss
Phenobarbital	epilepsy sedation, tolerance, dependence, CP450
Valproic acid	epilepsy GI distress, hepatotoxicity (rare but fatal), spina bifida teratogen, tremor, weight gain.
Ethosuxmide	epilepsy GI distress, fatigue, urticaria (hives), stevens-johnson syndrome
Benzodiazepines	Diazepam and Lorazepam, epilepsy Sedation, tolerance, dependence.
Tiagabine	epilepsy
Vigabatrin	epilepsy
Levetiracetam	epilepsy
Zolpidem	nonbenzo hypnotic
Zaleplon	nonbenzo hypnotic
Eszopiclone	nonbenzo hypnotic
Halothane	inhaled anesthetic, hepatotoxicity
Enflurane	inhaled anesthetic, proconvulsant
Isoflurane	inhaled anesthetic
Sevoflurane	inhaled anesthetic
Methoxyflurane	inhaled anesthetic, nephrotoxic
nitrous oxide	inhaled anesthetic, expansion of trapped gas
Thiopental	barpiturate, IV anesthetic, high potency and lipid soluble = rapid entry into brain. Short surgical procedures.
Midazolam	benzodiazepine IV anesthetic, Endoscopy. resp depression and amnesia
Ketamine	an arylcyclohexylamine / PCP analog. IV anesthetic. block NMDA recepto, cardiovascular stimulant, cause disorientation, bad dreams, hallucinations, increase brain blod flow.
propofol	iv anesthesia. rapid acting. use for short procedures. less perioperative nausea than thiopental (barbiturate)
Procaine	ester local anesthetic
Cocaine	ester local anesthetic arrythmia
tetracaine	ester local anesthetic
Lidocaine	Amide local ansthetic
Mepivacaine	Amide local anesthetic
Bupivacaine	Amide local anesthetic, cardiovascular toxicity
Succinylcholine	neuromuscular blocking drug - depolarizing
Tubocurarine	Neuromuscular blocking drug - non-deolarizing
Atracurium	Neuromuscular blocking drug - non-deolarizing
Mivacurium	Neuromuscular blocking drug - non-deolarizing
Pancuronium	Neuromuscular blocking drug - non-deolarizing
Vecuronium	Neuromuscular blocking drug - non-deolarizing
Rocuronium	Neuromuscular blocking drug - non-deolarizing
Neostigmine	cholinesterase inhibitor, reverses the blockade of non-depolarizing neuromuscular blocking drugs
Edrophonium	cholinesterase inhibitor, reverses the blockade of non-depolarizing neuromuscular blocking drugs
Dantrolene	Tx malignant hyperthermia. Prevents Ca2+ release from skeltal muscle SR. (malignant hyperthermia caused by inhaled anesthetics except NO)
Bromocriptine	dopamine receptor agonist, for parkinson's ergot = not preferred
pramipexole	dopamine receptor agonist, for parkinson's
ropinirole	dopamine receptor agonist, for parkinson's non-ergot = preferred
Amantidine	increase dopamine, for parkinson's antiviral for influenza A and rubella
L-dopa / Carbidopa	increase dopamine, for parkinson's (converted to dopamine in CNS)
Selegiline	Prevent dopamine breakdown, for parkinson's
Entacapone	Prevent dopamine breakdown, for parkinson's
Tolcapone	Prevent dopamine breakdown, for parkinson's
Benztropine	antimuscarinic (ach receptor), stops tremor in parkinson's
Memantine	Alzheimer's drug. NMDA receptor antagonist. prevents excitotoxicity. Dizziness, confusion, hallucination
Donepezil	ALzheimer's drug. Achesterase inhibitor
Galantamine	ALzheimer's drug. Achesterase inhibitor
Rivastigmine	ALzheimer's drug. Achesterase inhibitor
Reserpine + tetrabenazine	for Huntington's. Deplete amines. (dopamine is too high in huntington)
Haloperidol	For Huntinton's. dopamine receptor antagonist
Sumatripan	Serotonin agonist --> vasocontruction. Used for migraine and cluster headache attacks. Can cause coronary vasospasm, bad in prinzmetal's angina.