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Neuro Pharma
title
| Question | Answer |
|---|---|
| epinephrine | a-agonist, decrease aqueous humor production, don't use in angle closure because it will cause midriasis |
| brimonidine | a-agonist, decrease aqueous humor production |
| timolol | b-blcoker, decrease aqueous humor production |
| carteolol | b-blcoker, decrease aqueous humor production |
| betaxolol | b-blcoker, decrease aqueous humor production |
| acetazolimide | diuretic, decrease aqueous humor production |
| carbachol | direct cholinomimetic, increase aqueous humor drainage. Miosis |
| pilocarpine | direct cholinomimetic, increase aqueous humor drainage. Miosis |
| Echothiophate | indirect cholinomimetic, increase aqueous humor drainage. Miosis |
| physostigmine | indirect cholinomimetic, increase aqueous humor drainage. Miosis |
| Latanoprost | Prostaglandin, increase aqueous humor drainage, darkins pupul |
| Morphine | opiod analgesic also used IV as general anesthesia. |
| Methadone | opiod analgesic, pulm edema and drug addiction |
| Meperidine | opiod analgesic |
| Fentanyl | opioid analgesic also used iv as general anesthetia |
| Codeine | opioid analgesic |
| Heroin | opioid analgesic |
| Dextromethorphan | opioid analgesic, pain and cough |
| Diphenoxylate | opioid analgesic, diarrhea |
| Naloxone | opiod antagonist |
| Naltrexone | opioid antagonist |
| Butorphanol | partial mu and kappa opiod agonist, causes less resp depression but used for pain. |
| Tramadol | weak opioid agonist, many neurotranmitters, decreases seizure threshold |
| Phenytoin | epilepsy nystagmus, dilopia, ataxia, sedation, gingival hyperplasia, hirsutism, megaloblastic anemia, teratogenesis, SLE-like sx, CP450 |
| Carbamazepine | epilepsy Diplopia, ataxa, blood dyscrasia, lover toxic, teratogen, CP450, SIADH, stevens-johnson syndrome |
| Lamotrigine | epilepsy stevens-johnson syndrome |
| GABApentin | epilepsy sedation, ataxia |
| Topiramate | epilepsy sedatio, mental dulling, kidney stones, weight loss |
| Phenobarbital | epilepsy sedation, tolerance, dependence, CP450 |
| Valproic acid | epilepsy GI distress, hepatotoxicity (rare but fatal), spina bifida teratogen, tremor, weight gain. |
| Ethosuxmide | epilepsy GI distress, fatigue, urticaria (hives), stevens-johnson syndrome |
| Benzodiazepines | Diazepam and Lorazepam, epilepsy Sedation, tolerance, dependence. |
| Tiagabine | epilepsy |
| Vigabatrin | epilepsy |
| Levetiracetam | epilepsy |
| Zolpidem | nonbenzo hypnotic |
| Zaleplon | nonbenzo hypnotic |
| Eszopiclone | nonbenzo hypnotic |
| Halothane | inhaled anesthetic, hepatotoxicity |
| Enflurane | inhaled anesthetic, proconvulsant |
| Isoflurane | inhaled anesthetic |
| Sevoflurane | inhaled anesthetic |
| Methoxyflurane | inhaled anesthetic, nephrotoxic |
| nitrous oxide | inhaled anesthetic, expansion of trapped gas |
| Thiopental | barpiturate, IV anesthetic, high potency and lipid soluble = rapid entry into brain. Short surgical procedures. |
| Midazolam | benzodiazepine IV anesthetic, Endoscopy. resp depression and amnesia |
| Ketamine | an arylcyclohexylamine / PCP analog. IV anesthetic. block NMDA recepto, cardiovascular stimulant, cause disorientation, bad dreams, hallucinations, increase brain blod flow. |
| propofol | iv anesthesia. rapid acting. use for short procedures. less perioperative nausea than thiopental (barbiturate) |
| Procaine | ester local anesthetic |
| Cocaine | ester local anesthetic arrythmia |
| tetracaine | ester local anesthetic |
| Lidocaine | Amide local ansthetic |
| Mepivacaine | Amide local anesthetic |
| Bupivacaine | Amide local anesthetic, cardiovascular toxicity |
| Succinylcholine | neuromuscular blocking drug - depolarizing |
| Tubocurarine | Neuromuscular blocking drug - non-deolarizing |
| Atracurium | Neuromuscular blocking drug - non-deolarizing |
| Mivacurium | Neuromuscular blocking drug - non-deolarizing |
| Pancuronium | Neuromuscular blocking drug - non-deolarizing |
| Vecuronium | Neuromuscular blocking drug - non-deolarizing |
| Rocuronium | Neuromuscular blocking drug - non-deolarizing |
| Neostigmine | cholinesterase inhibitor, reverses the blockade of non-depolarizing neuromuscular blocking drugs |
| Edrophonium | cholinesterase inhibitor, reverses the blockade of non-depolarizing neuromuscular blocking drugs |
| Dantrolene | Tx malignant hyperthermia. Prevents Ca2+ release from skeltal muscle SR. (malignant hyperthermia caused by inhaled anesthetics except NO) |
| Bromocriptine | dopamine receptor agonist, for parkinson's ergot = not preferred |
| pramipexole | dopamine receptor agonist, for parkinson's |
| ropinirole | dopamine receptor agonist, for parkinson's non-ergot = preferred |
| Amantidine | increase dopamine, for parkinson's antiviral for influenza A and rubella |
| L-dopa / Carbidopa | increase dopamine, for parkinson's (converted to dopamine in CNS) |
| Selegiline | Prevent dopamine breakdown, for parkinson's |
| Entacapone | Prevent dopamine breakdown, for parkinson's |
| Tolcapone | Prevent dopamine breakdown, for parkinson's |
| Benztropine | antimuscarinic (ach receptor), stops tremor in parkinson's |
| Memantine | Alzheimer's drug. NMDA receptor antagonist. prevents excitotoxicity. Dizziness, confusion, hallucination |
| Donepezil | ALzheimer's drug. Achesterase inhibitor |
| Galantamine | ALzheimer's drug. Achesterase inhibitor |
| Rivastigmine | ALzheimer's drug. Achesterase inhibitor |
| Reserpine + tetrabenazine | for Huntington's. Deplete amines. (dopamine is too high in huntington) |
| Haloperidol | For Huntinton's. dopamine receptor antagonist |
| Sumatripan | Serotonin agonist --> vasocontruction. Used for migraine and cluster headache attacks. Can cause coronary vasospasm, bad in prinzmetal's angina. |