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Neuro Pharma
title
Question | Answer |
---|---|
epinephrine | a-agonist, decrease aqueous humor production, don't use in angle closure because it will cause midriasis |
brimonidine | a-agonist, decrease aqueous humor production |
timolol | b-blcoker, decrease aqueous humor production |
carteolol | b-blcoker, decrease aqueous humor production |
betaxolol | b-blcoker, decrease aqueous humor production |
acetazolimide | diuretic, decrease aqueous humor production |
carbachol | direct cholinomimetic, increase aqueous humor drainage. Miosis |
pilocarpine | direct cholinomimetic, increase aqueous humor drainage. Miosis |
Echothiophate | indirect cholinomimetic, increase aqueous humor drainage. Miosis |
physostigmine | indirect cholinomimetic, increase aqueous humor drainage. Miosis |
Latanoprost | Prostaglandin, increase aqueous humor drainage, darkins pupul |
Morphine | opiod analgesic also used IV as general anesthesia. |
Methadone | opiod analgesic, pulm edema and drug addiction |
Meperidine | opiod analgesic |
Fentanyl | opioid analgesic also used iv as general anesthetia |
Codeine | opioid analgesic |
Heroin | opioid analgesic |
Dextromethorphan | opioid analgesic, pain and cough |
Diphenoxylate | opioid analgesic, diarrhea |
Naloxone | opiod antagonist |
Naltrexone | opioid antagonist |
Butorphanol | partial mu and kappa opiod agonist, causes less resp depression but used for pain. |
Tramadol | weak opioid agonist, many neurotranmitters, decreases seizure threshold |
Phenytoin | epilepsy nystagmus, dilopia, ataxia, sedation, gingival hyperplasia, hirsutism, megaloblastic anemia, teratogenesis, SLE-like sx, CP450 |
Carbamazepine | epilepsy Diplopia, ataxa, blood dyscrasia, lover toxic, teratogen, CP450, SIADH, stevens-johnson syndrome |
Lamotrigine | epilepsy stevens-johnson syndrome |
GABApentin | epilepsy sedation, ataxia |
Topiramate | epilepsy sedatio, mental dulling, kidney stones, weight loss |
Phenobarbital | epilepsy sedation, tolerance, dependence, CP450 |
Valproic acid | epilepsy GI distress, hepatotoxicity (rare but fatal), spina bifida teratogen, tremor, weight gain. |
Ethosuxmide | epilepsy GI distress, fatigue, urticaria (hives), stevens-johnson syndrome |
Benzodiazepines | Diazepam and Lorazepam, epilepsy Sedation, tolerance, dependence. |
Tiagabine | epilepsy |
Vigabatrin | epilepsy |
Levetiracetam | epilepsy |
Zolpidem | nonbenzo hypnotic |
Zaleplon | nonbenzo hypnotic |
Eszopiclone | nonbenzo hypnotic |
Halothane | inhaled anesthetic, hepatotoxicity |
Enflurane | inhaled anesthetic, proconvulsant |
Isoflurane | inhaled anesthetic |
Sevoflurane | inhaled anesthetic |
Methoxyflurane | inhaled anesthetic, nephrotoxic |
nitrous oxide | inhaled anesthetic, expansion of trapped gas |
Thiopental | barpiturate, IV anesthetic, high potency and lipid soluble = rapid entry into brain. Short surgical procedures. |
Midazolam | benzodiazepine IV anesthetic, Endoscopy. resp depression and amnesia |
Ketamine | an arylcyclohexylamine / PCP analog. IV anesthetic. block NMDA recepto, cardiovascular stimulant, cause disorientation, bad dreams, hallucinations, increase brain blod flow. |
propofol | iv anesthesia. rapid acting. use for short procedures. less perioperative nausea than thiopental (barbiturate) |
Procaine | ester local anesthetic |
Cocaine | ester local anesthetic arrythmia |
tetracaine | ester local anesthetic |
Lidocaine | Amide local ansthetic |
Mepivacaine | Amide local anesthetic |
Bupivacaine | Amide local anesthetic, cardiovascular toxicity |
Succinylcholine | neuromuscular blocking drug - depolarizing |
Tubocurarine | Neuromuscular blocking drug - non-deolarizing |
Atracurium | Neuromuscular blocking drug - non-deolarizing |
Mivacurium | Neuromuscular blocking drug - non-deolarizing |
Pancuronium | Neuromuscular blocking drug - non-deolarizing |
Vecuronium | Neuromuscular blocking drug - non-deolarizing |
Rocuronium | Neuromuscular blocking drug - non-deolarizing |
Neostigmine | cholinesterase inhibitor, reverses the blockade of non-depolarizing neuromuscular blocking drugs |
Edrophonium | cholinesterase inhibitor, reverses the blockade of non-depolarizing neuromuscular blocking drugs |
Dantrolene | Tx malignant hyperthermia. Prevents Ca2+ release from skeltal muscle SR. (malignant hyperthermia caused by inhaled anesthetics except NO) |
Bromocriptine | dopamine receptor agonist, for parkinson's ergot = not preferred |
pramipexole | dopamine receptor agonist, for parkinson's |
ropinirole | dopamine receptor agonist, for parkinson's non-ergot = preferred |
Amantidine | increase dopamine, for parkinson's antiviral for influenza A and rubella |
L-dopa / Carbidopa | increase dopamine, for parkinson's (converted to dopamine in CNS) |
Selegiline | Prevent dopamine breakdown, for parkinson's |
Entacapone | Prevent dopamine breakdown, for parkinson's |
Tolcapone | Prevent dopamine breakdown, for parkinson's |
Benztropine | antimuscarinic (ach receptor), stops tremor in parkinson's |
Memantine | Alzheimer's drug. NMDA receptor antagonist. prevents excitotoxicity. Dizziness, confusion, hallucination |
Donepezil | ALzheimer's drug. Achesterase inhibitor |
Galantamine | ALzheimer's drug. Achesterase inhibitor |
Rivastigmine | ALzheimer's drug. Achesterase inhibitor |
Reserpine + tetrabenazine | for Huntington's. Deplete amines. (dopamine is too high in huntington) |
Haloperidol | For Huntinton's. dopamine receptor antagonist |
Sumatripan | Serotonin agonist --> vasocontruction. Used for migraine and cluster headache attacks. Can cause coronary vasospasm, bad in prinzmetal's angina. |