Question | Answer |
Cyst? | abnormal cavity in hard or soft tissue, which contains fluid or semi-soft fluid and is often encapsulated and lined with epithelium |
Why does a cyst form? | Body’s attempt to protect the area of tissue |
Why during inflammation—caries leading to necrosis of the pulp? | Epithelium grows and forms a distinct circle, and eventually closes itself from the surrounding tissue
Cyst fills with fluid and expands |
what does osteoclasts do? | Absorb bone |
Odontogenic cyst? | cysts with an epithelial lining composed of remnants of the tooth-forming organ that arise primarily in tissue and bone |
Non-odontogenic cyst? | abnormal closed epithelium-lined cavity in the body, containing gas, serous/liquid or semisolid material. |
Pseudocyst? | an abnormal or dilated space resembling a cyst but not lined with epithelium |
Periapical granuloma? etiology? | result of necrotic pulp tissue and by-products resulting from inflammatory process that has damaged the tissue at the apex of the tooth
i-e trauma, perio disease, fracture. |
Pathogenesis of Periapical Granuloma | diseased tissue causes granulation tissue to accumulate at the apex of the tooth; pulp becomes necrotic (irreversible pulpitis);
poss. nonvital tooth |
Location of periapical Granuloma | Apex of the tooth |
radiographic appearance of Periapical Granuloma | round or ovoid translucent lesion |
Cells in Periapical Granuloma that help to fight infection? | Plasma cells, neutrophils, macrophages, eosinophils |
Radicular cyst/“periapical cyst” | Always associated with a nonvital tooth |
Common causes of Radicular cyst?
Location? | caries, trauma, periodontal disease
apex of a nonvital tooth; favors the mx anterior teeth |
Epidemiology of Radicular Cyst? | most commonly occurring inflammatory cyst/tooth cyst of the jaw; adults; mean age of 30 |
Microscopic features of Radicular cyst? | non-keratinized epithelial lining w/necrotic debris & inflammation infiltrate |
Pathogenesis of Radicular cyst?
radiographically? | Derived from the rests of Malassez of perio ligament
blunting of the root (resorption) |
Aneurysmal bone cyst? | Benign lesion/pseudocyst that is blood filled
A localized dilatation of an artery or a vein |
Pseudocysts? | False cyst |
where does aneurysmal bone cyst arises from? | prior trauma or some genetic components |
Aneurysmal bone cyst is seen in? | less than 30 years of age; sl. more females |
radiographic characteristics and tx of Aneurysmal bone cyst? | unilocular or mutilocular lesions
removal of lesion and curettage |
Traumatic bone cyst? | Simple bone cyst
thought to be caused by trauma |
Epidemiology and pathogenesis of traumatic bone cyst?
location? | 10-20 year old age group
may be empty or filled with a small amount of fluid (blood & bone products)
Mand. |
Radiographic charac. of Traumatic bone cyst? | "scalloping cyst” or scalloping between teeth; honeycomb appearance |
Cemento-osseous dysplasia Etiology? | unknown but condition is considered reactive or developmental (related to a defect in the bone and/or cementum remolding) |
Cemento? | Cementum |
Osseous | Bone |
Where can Cemento-osseous dysplasia develop? | Can develop in mandibular area, posterior area. |
Microscopic Features of Cemento-osseous dysplasia? | contains fibrous connective tissue that can be seen with bone and cementum in varying amounts |
Location of Cemento-osseous dysplasia? | Apex of the vital teeth |
Static (Stafne) bone cyst? | defect in the mandible that surrounds salivary gland tissue |
Location of Static bone cyst? | inferior to the md canal and happens during development |
static? | lacking in movement, action, or change, especially in a way viewed as undesirable or uninteresting. |
Lateral Periodontal Cyst?
Epidemiology?
Location? | odontogenic, nonkeratinized developmental cyst
30 years and older; > males
md premolar-canine; on lateral surface
Asymptomatic but adjacent teeth are vital |
Dentigerous Cyst? | Second most common cyst of the jaw
arises from a cystic change in the dental follicle following crown formation
forms around crowns of unerupted tooth |
Pathogenesis of Dentigerous Cyst? | fluid between formed crown and reduced enamel epithelium |
Location of Dentigerous Cyst? | cyst is attached at CEJ; most common location is unerupted third molars; impacted, odontoma, supernumerary teeth |
Eruption cyst/“eruption hematoma” | caused by the accumulation of fluid and blood between the crown of an erupting tooth and the reduced enamel organ, due to trauma |
Epidemiology/location/Clinical characteristics of Dentigerous Cyst? | deciduous teeth and perm molars of children
crest of alveolar ridge/gingiva
bluish swelling of the tissue with a dome-shape |
Odontogenic Keratocyst (OKC)? | Develops from dental lamina or its remnants. more common in male |
Location of OKC? | Posterior mandibular location is frequent (can occupy most of the ramus) |
Clinical Characteristics of OKC? | large enough to displace teeth and extend through the cancellous bone into the oral cavity; as jaw weakens it may fracture |
Calcifying Odontogenic Cyst? | calcifying cyst derived from reduced-enamel epithelium or dental lamina remnants |
Radiographic Calcifying Odontogenic Cyst? | radiodencities (calcified material) and radiolucent properties |
Microscopic feature of Calcifying Odontogenic Cyst? | ghost cells”, epithelial cells that appear to have pink cytoplasm and have no nucleus; calcifications seen |
Gingival Cyst?
Clinical characteristics?
Location? | Nodules are multiple small cysts that disappear and rupture over time
Md canine / premolar area. soft tissue/gingiva |
Nasopalatine/incisive Canal Cyst? | arises from epithelial remnants of the embryologic structure of the nasopalatine ducts. adults 40-60 year old, males |
location of Nasopalatine/incisive Canal Cyst?
radiographically? | nasopalatine canal; between the mx central incisors
heart-shaped |
Median Palatine Cyst? | Rare fissural cyst believed to develop from entrapped epithelium along the embryonic line of fusion in the two lateral mx processes that fuse to make the hard palate. |
Location of Median Palatine Cyst? | apically centered toward the midline hard palate |
Median Mandibular Cyst? | Rare
Midline of mandible
Well-defined radiolucency below apices of md incisors
Surgical excision |
Adenomatoid odontogenic tumor? | Benign neoplasm of epithelial tissue; epithelial odontogenic tumor with a dense fibrous connective tissue capsule. facial swelling |
Location/epidemiology of Adenomatoid odontogenic tumor? | usually surrounds the crown of a tooth/impacted tooth; anterior mx. seen in an adolescent or young adult; females |
Odontogenic myxoma? | Derived from odontogenic ectomesenchyme, and it originates in the periodontal ligament or dental pulp. capable of rapid growth . Root resorption and displacement may be seen in some cases |
Myxomas have also been described as? | “step ladder” or “honeycombed” appearance. |
Ameloblastic fibroma? | The lesions are composed of neoplastic epithelium and neoplastic myxomatous connective tissue and are usually associated with third molars.
mixed odontogenic tumor; rare |
Perioral and Intraoral Characteristics of Ameloblastic fibroma? | no pain with any swelling that may occur.
has potential for extensive growth causing jaw expansion. |