| Question | Answer | Derivatives |
| sacer sacra, sacrum | sacred, holy; sacrifices [n. pl.] | (desecrate, consecrate) |
| saevus -a, -um | savage, fierce, ferocious | (savage) |
| salūs salūtis (F) | well-being, safety; greeting | (salutation) |
| sanguis sanguinis (M) | blood; bloodshed; descent, lineage | (sanguine) |
| saxum -ī (N) | boulder, stone, large rock | (saxifrage) |
| scopulus -ī (M) | cliff, crag, rock; ledge | () |
| se recipere | to go [lit. take oneself] | () |
| sed (conj.) | but | () |
| sēdēs sēdis (F) | seat; dwelling; foundation | (sedate; sedentary) |
| Sēquanī -ōrum (M pl.) | Sequani [a people of Gaul, west of the Jura mountains] | (Sequani) |
| servō -āre, -āvī, -ātum | to save, guard, keep; to watch | (conservation, reserve) |
| sī (conj.) | if; when; whether | () |
| sīc (adv.) | thus, in this way | () |
| sīdus sīderis (N) | constellation; star; sky, heavens; weather | (consider, sidereal) |
| silva -ae (F) | forest, woods | (sylvan, Pennsylvania) |
| simul (adv.) | at the same time, simultaneously, together | (simulcast, simultaneous) |
| sine (prep. w/ abl.) | without | (sinecure) |
| socius -ī (M) | ally, friend, comrade | (society, socialism) |
| somnus -ī (M) | sleep | (insomnia, somniferous) |
| soror -ōris (F) | sister | (sorority, sororicide) |
| sors sortis (F) | luck, lot; fate, destiny | (consort, consortium) |
| spērō -āre, -āvī, -ātum | to hope; to look for, expect | (despair, prosper) |
| spēs speī (F) | hope, expectation | (despair) |
| stō stāre, stetī, stātum | to stand; to be built; to linger, remain | (stance, stature) |
| sub (prep. w/ acc. & w/ abl.) | under; up to | (subordinate, submarine) |
| subeō subīre, subiī, subitum | to come up | () |
| subitō (adv.) | suddenly | () |
| subsequor -ī, subsecūtus sum | to follow closely | (subsequent) |
| subsidium -ī (N) | reserve troops; aid, support | (subsidize) |
| sum esse, fuī, futūrum | to be; to exist | (essence, essential) |
| summus -a, -um | highest, loftiest, supreme, the top of | (summit, summary) |
| superior superius | upper, higher; previous; more | (superiority, superlative) |
| superō -āre, -āvī, -ātum | to defeat; to prevail; to survive; to overcome | () |
| surgō -ere, surrexī, surrēctum | to rise, get up | (surge) |
| sustineō -ēre, -uī, sustentum | to uphold, sustain | (sustinence) |
| suus -a, -u | his, her, its, their (own) | (suicide, sui generis) |
| tālis tāle | such, of such a kind | () |
| tamen (adv.) | nevertheless, however, still | () |
| tandem (adv.) | finally, at last | (tandem) |
| tantum (adv.) | so much, so greatly; only | (tantamount) |
| tantus . . . quantus | so great . . . as | () |
| tantus -a, -um | so great, so much, so large | (tantamount) |
| tēctum -ī (N) | roof; house, dwelling | (protect, detect, tegument) |