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Pharm Test 3

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Created by: 10212282533089527

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Fluid and Electrolytes

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Cardiovascular Pharmacology

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(-) roots and meanings end of word

1 A Cardiac Rhythym Strip Analysis

Term	Definition
Enalapril	Vasotec Ace Inhibitor
Enalapril Indications	HTN HF
Enalapril Interactions	Other HTN meds = additive Thiazide = increase K loss Increase lithium toxicity NSAIDs= decrease effects = Increase BP
Enalapril CI	Hypersensitivity Pregnancy/Lactation BBW= Fetal injury/death
Enalapril SE	OTH 1st dose syncope HA/Dizziness LIFETHREATENING: angioedema, neutropenia, agranulocytosis
Nifedipine	Procardia CCB
Nifedipine Indications	HTN Angina
Nifedipine Interactions	Other HTN meds= additive BB= increase risk of HF Increase Dig toxocity Alcohol=syncope Grapefruit juice=enhance absorption= additive Melatonin=counter effects = increase BP/HR
Nifedipine CI	Hypersensitivity
Nifedipine SE	HA Dizziness Peripheral Edema Flushing *Immediate action forms= reflex tachycardia DC gradually=rebound hypotension
Doxazosin	Cardura A Blocker
Doxazosin Indications	Urinary Retention--> BPH & HTN
Doxazosin Interactions	Other HTN meds= additive Climetidine=increase half life Viagra (phosphodiesterase inhib) = additive
Doxazosin CI	Hypersensitivity Hypotensive
Doxazosin SE	Dizziness Dyspnea Athenia HA Hypotension Somnolence OTH 1st does phenomenon
Metoprolol	Lopressor BB
Metoprolol Indications	HTN HF
Metoprolol Interactions	Diuretics + antiHTN= mask hypoglycemia NSAID=decrease effect Digoxin= increase risk of bradycardia Oral contraceptives = increase effects
Metoprolol CI	Hypersensitivity MI= serious sinus bradycardia HR <45/ SBP <100 Mod-Severe HF Asthma Cardiogenic shock
Metoprolol SE	Diminished sexual function Insomnia Unusual weakness/fatigue
Losartan	Cozaar ARB
Losartan Indication	HTN
Losartan Interactions	NSAIDs= decrease K diuretics = increase K Diuretics/ antiHTN= additive Herbal: ephedra, licorice, ginseng= additive
Losartan CI	Hypersensitivity Renal/Hepatic impairment K supplements- hyperkalemia Hx of angioedema
Losartan SE	HA Dizziness OTH Rash Diarrhea AE= angioedema, acute renal failure, 1st dose phenomenon, fetal toxicity, neonatal mortality
Hydralazine	Apresoline Vasodilator
Hydralazine Indication	HTN HF
Hydralazine Interactions	Other HTN meds= additive NSAID= decrease False coombs test Hawthorn= decrease
Hydralazine CI	Angina Rheumatic Heart Dz MI Tachycardia Lupus= worsens Abrupt wd= rebound HTN
Hydralazine SE	HA Tachycardia Palpitations Flushing Nausea Diarrhea BB=counteract reflex tachycardia *Na/fluid retenion= serious AE
Furosemide	Lasix Loop diuretic
Furosemide Indications	HTN HF (if fluid retention present)
Furosemide Interactions	Cardiac glycosides (dig)= hypokalemia Corticosteroids, amp B, K depleting drugs = hypokalemia
Furosemide CI	Hypersensitivty Anuria Hepatic Coma Severe fluid/electrolyte depletion
Furosemide SE	Hypokalemia Dehydration Hypotension OTH *Ototoxicity
Spironolactone	Aldactone K sparing diuretic, Aldosterone antagonist
Spironolactone Indications	HTN Edema- HF
Spironolactone Interactions	Ammonium chloride= acidosis ASA, NSAIDs= decrease Digoxin= decrease effects of dig K supplements, ACE inhibitors, ARBS= hyperkalemia
Spironolactone CI	Anuria Renal impairment Hyperkalemia Pregnancy/Lactation
Spironolactone SE	Hyperkalemia Women: menstrual irregularities, hirsutism, breast tenderness
Hydrochlorothiazide	Microzide Thiazide diuretic
Hydrochlorothiazide Indication	HTN Edema-HF
Hydrochlorothiazide Interactions	Other HTN med= additive Decrease effectivess of anticoag, sulfonylureas, antidiabetic drugs Cholestryamine and Colestipol= decrease absorption NSAIDS= renal toxicity Corticosteroids, amp B = increase K loss= hypokalemia
Hydrochlorothiazide CI	Anuria Hypersensitivity Pre-eclampsia Eclampsia Pregnancy induced HTN
Hydrochlorothiazide SE	Na/K imbalances Teach increase K in diet Gout attacks= due to hyperuricemia
Digoxin	Lanoxin Cardiac Glycoside
Digoxin Indication	HF
Digoxin Interactions	Diuretics=hypokalemia= dysrhythmias Ace inhib, spironolactone, ARB= hyperkalemia Positive inotropic drug= additive BB= additive bradycardia Antacids, cholesterol lowering drugs= decrease absorption Ginseng= increase risk of dig tox Ma huang, ephedra
Lisinopril	Prinivil Ace Inhib
Lisinopril Indications	HTN HF
Lisinopril Interactions	NSAIDS= decrease Diuretic= additive K diuretic= hyperkalemia Increase lithium levels= toxicity
Lisinopril CI	Hyperkalemia Angioedema Pregnancy
Lisinopril SE	Cough HA Dizziness OTH Rash Hyperkalemia Taste disturbances Chest pain N/V/D Angioedema= SERIOUS