Question | Answer |
Which class of ABx is Sulfamethoxazole? | Sulfonamides: Bacteriostatic
Prevent synthesis of folic acid |
Which class of ABx is Sulfisoxazole | Sulfonamides: Bacteriostatic
Prevent synthesis of folic acid |
What are Adverse Effects of Sulfonamides? | Hemolytic and aplastianemia, agranulocytosis, thrombocytopenia Photosensitivity, exfoliative dermatitis, SJS epidermal necrolysis
N&V, Diarrhea, pancreatitis, convulsions, cephalgia, liver and kidney problems |
What is the prototype of the sulfonamides class? | Cotrimoxazole- Indications- UTI, Acut OM, chronic bronchitis, traveler's diarrhea
Orall route, rapid abosobtion |
What are 4 major sub-classes of Beta Lactam Antibiotics? | Penicillins, cephalosporins, carbapenems, and monobactams |
When was penicillin first introduced? | 1940 |
What broad spectrum antibiotic is bactericidal (inhibits cell wall synthesis) | Penicillin |
What enzyme do some bacteria produce to become resistant to penicillins? | B-lactamase |
Which types of bacteria is susceptible to PCN? | gram positive |
What other sub-class of Beta Lactams is a patient also likely to be allergic to if they have an allergy to PCN? | Cephalosporins |