Question | Answer |
class thioridizine | typical antipsychotic |
class haloperidol | typical antipsychotic |
class fluphenazine | typical antipsychotic |
class chlorpromazine | typical antipsychotic |
class clozapine | atypical antipsych |
Class olazapine | atypical antipsych |
class risperidone | atypical antipsych |
class fluoxetine | ssri |
class paroxetine | ssri |
class sertraline | ssri |
class citalpram | ssri |
class imipramine | tca |
class amitriptyline | tca |
class desipramine | tca |
class nortiptyline | tca |
class clomipramine | tca |
class doxepin | tca |
class buprorpion | heterocyclic |
class venlafaxine | heterocyclic |
class mirtazapine | heterocyclic |
class maprotiline | heterocyclic |
class trazadone | heterocyclic |
class phenylzine | maoi |
class tranylcypromine | maoi |
toxicity associated with ssri | gi distress anorgasmi a seratonin syndrome if given with maoi |
sx of seratonin syndrome | hyperthermia muscle rigidity cv collapse |
how long does it take for antidepressants to work | 2-3 wks |
side effects of tca | sedation alpha-blocking effects atropine like effects (tachy, urinary retention) |
which generation of tca s have more anticholinergic effects? give an example of the drug | 3rd amitryptyline |
which tca is least sedating | desipramine |
toxicity assocaited with tcas | tri-c's convulsions coma cardiotoxicity respiratory depression hyperpyrexia confusion and hallucination in elderly (d/t anticholinergic effects) |
which class of drugs is used to treat alcohol w/d | benzos |
which class of drugs is used to treat anorexia/bulemia | ssri |
which drugs are used to treat anxiety | buspirone benzos/barbiturates (take a shorter time to work) MAOI |
which drugs are ssris? | paroxetine fluoxetine sertriline citalopram |
which class of drugs is used to treat atypical depression | maoi |
which class of drugs is used ot treat bipolar d/o | lithium carbamazepine valproic acid |
which drugs are used to treat depression | ssri tca |
which drugs are used to treat depression with insomnia | trazadone mirtazapine |
which drugs are used totreat OCD | climipramine ssri olanzepine |
which drugs are used to treat panic d/o | tca buspirone |
toxicity associated with maois | hypertensive crisis associated with ingesting wine/cheese (tyramine) |
drug interactions assicated with maois | TCA and ssri (--> both cause seratonin syndrome) |
MOA venlafaxine | inhibits 5HT, NorE, |
toxicity of venlafaxine | stimulant effects sedation nausea constipation increased BP |
MOA mirtazapine | alpha-2 antagonist (increased release of NorE and 5HT) and potent 5HT2, 3 receptor antagonist |
toxicity of mirtazapine | sedation increased appetite weight gain dry mouth |
moa maprotiline | blocks NorE reuptake |
toxicity of maprotiline | sedation orthostatic hypotension |
moa trazadone | inhibits 5HT reuptake |
toxicity of trazadone | sedation nausea priapism postural hypotension |
MOA dantroline | blocks the release of ca from SR of skeletal muscles |
uses of dantroline | nms malignant hyperthermia |
wha tcan cause malignant hyperthermia | inhalation of anesthetics and succinylcholine |
what are the different types of NM blocking agents | depolarizing and nondepolarizing |
ex of a depolarizing NM blocking agent | succinylcholine |
ex of nondepolarizing NM blockign agent | anything with a "cur" in it |
uses of NM blockign agents | to paralyze muscles in surgery or mechanical ventilation |
what are the 2 phases of depolarizing NM blockade? | 1: continuous depolarization 2: gradual repolarization with resistance |
how do you reverse the depolarizing blockade at phase 1? phase 2? | administer cholinesterase inhibitors (eg: neostigmine or physostimine) during PHASE |
how do you reverse the non-depolarizing blockade? | cholinesterase inhibitors (eg: neostigmine, edrophonium) |