Name | Receptor | Used in |
Acetylcholine (ACh) | muscarinic and nicotinic agonist. | neurotransmitter |
Adrenaline | non-selective adrenoreceptor agonist. | cardiac arrest
anaphylaxis (allergic rxn) |
Atropine | non-selective muscarinic agonist | premedication before surgery
bardycardia (low BPM)
GI spasms
anticholinesterase poisoning |
Bethanecol | non-selective muscarinic agonist | urinary retension
constipation
-relaxes muscles |
Botox | exocytosis blocker
selective cholinergic uptake | hyperhydrosis (increased sweating/perspiration)
muscle spasm |
Butoxamine | β2-adrenoceptor antagonist | experimental pharmacology |
Carbachol | (synthetic) muscarinic and nicotinic agonist | relaxes smooth muscle
eye/ophthalmic purposes like glaucoma |
Carbidopa | inhibitor of DOPA decarboxylase | Parkinsons |
Clonidine | partial α2-adrenoceptor agonist | hypertension (high BP) |
Darifenacin | M3-selective muscarinic antagonist | reduce urinary frequency |
Diclyomine | non-selective muscarinic antagonist | irritable bowel syndrome |
Distigmine | medium duration anticholinesterase | inhibits breakdown of ACh in synapse, so prolongs it's effecs on the postsynaptic receptors |
Dobutamine | β1-adrenoceptor agonist | cardiogenic shock
cardiac surgery |
Ecothiopate | irreversible anticholinesterase | glaucoma (eye drops - reduce intraocular pressure within eye) |
Ephedrine | indirectly acting sympathomimetic | nasal congestion - relaxes airways
stimulant - speeds up heart and nervous system |
Guanethidine | blocks NA realease | hypertensive crisis (high BP, impairing 1+ major organ system) |
Hemicholinium | presynaptic ACh uptake blocker | decreases production of ACh - so is an indirect ACh antagonist.
No clinical use - but used in research experiments |
Hyoscine | non-selective muscarinic antagonist | premedication before surgery
GI spasms
motion sickness |
Ipratropium | non-selective muscarinic antagonist | asthma - relaxes airways by inhibiting constriction of smooth muscles |
Isoprenaline | non-selective β-adrenoceptor agonist | shock |
Labetalol | non-selective α1, β1-2 antagonist | hypertension (high BP) |
Methyldopa | partial α2-adrenoceptor agonist precursor | hypertension (high BP) in pregnancy |
Muscarine | non-selective muscarinic agonist | favours rest and digest |
Neostigmine | medium duration anticholinesterase | constipation - contracts GI tract smooth muscles |
Nicotine | nicotinic AChR agonist | |
Noradrenaline (NA) | non-selective adrenoceptor agonist | neurotransmitter |
Oxotremorine | non-selective muscarinic agonist | experimental pharmacology |
Phenoxybenzamine | irreversible α-adrenoceptor antagonist | phaeochromocytoma (tumour at adrenal medulla - extra chromaffin tissue, so more NA/Adrenaline) |
Phentolamine | α-adrenoceptor antagonist | phaeochromocytoma (tumour at adrenal medulla - extra chromaffin tissue, so more NA/Adrenaline) |
Phenylephrine | α1-adrenoceptor agonist | nasal congestion
acute hypertension (high BP) |
Pilocarpine | non-selective muscarinic agonist | glaucoma
dry eyes
mouth |
Pirenzepine | M1-selective muscarinic antagonist | peptic ulcer |
Prazosin | α1-adrenoceptor antagonist | hypertension (high BP)
prostatic hyperplasia (enlarged prostate) |
Propanolol | non-selective β-adrenoceptor antagonist | hypertension (high BP)
anxiety
migraine |
Reserpine | vesicular monoamine uptake blocker | experimental
can cause depression/hypotension |
Salbutamol | β2-adrenoceptor agonist | asthma (short term)
premature labour |
Salmeterol | β2-adrenoceptor agonist | asthma prophylaxis |
Timolol | non-selective β-adrenoceptor antagonist | hypertension
angina
migraine
glaucoma |
Tropicamide | non-selective (but M4 prefering) muscarinic antagoninst | eye examinations |
Tyramine | amino acid responsible for cheese reaction | |
Vesamicol | vesicular ACh uptake blocker | |
Yohimbine | α2-adrenoceptor antagonist | aphrodisiac? |
α-Methyltyrosine | inhibitor of tyrosine kinase | |
Atenolol | β1-adrenoceptor antagonist. | hypertension (high BP)
angina (narrowing of coronal arteries)
arrhythima (irregular heart beat) |